Literature DB >> 10103699

Heparin versus saline flushing solutions in a small community hospital.

P J Barrett1, R L Lester.   

Abstract

Since no nursing policy on flushing procedures existed in their small community hospital, the authors thought it would be useful to clarify recent reports of the equivalency of saline to heparin flushes in their patient group before establishment of such a policy. They conducted a 2 month double-blinded, cross-over study of catheter failures when using either saline or heparin 10 units/mL flushing solutions. All medical and surgical floor patients were included in the study. Floor nurses were used as observers and characterized catheter failures as either loss of patency or phlebitis. Heparin was shown to cause more phlebitis than saline (p less than .025), but no difference was found between the two flushing solutions in loss of patency. Data revealed a statistically significant advantage to using saline flushes when both loss of patency and phlebitis were combined (p less than .05). They recommended adoption of a flushing procedure which did not contain heparin.

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Year:  1990        PMID: 10103699

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN: 0018-5787


  5 in total

1.  Benefit of heparin in peripheral venous and arterial catheters: systematic review and meta-analysis of randomised controlled trials.

Authors:  A G Randolph; D J Cook; C A Gonzales; M Andrew
Journal:  BMJ       Date:  1998-03-28

Review 2.  Interventions for restoring patency of occluded central venous catheter lumens.

Authors:  Clare van Miert; Rebecca Hill; Leanne Jones
Journal:  Cochrane Database Syst Rev       Date:  2012-04-18

Review 3.  Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults.

Authors:  Eduardo López-Briz; Vicente Ruiz Garcia; Juan B Cabello; Sylvia Bort-Martí; Rafael Carbonell Sanchis
Journal:  Cochrane Database Syst Rev       Date:  2022-07-18

4.  Comparison of heparinized saline and 0.9% sodium chloride for maintaining central venous catheter patency in healthy dogs.

Authors:  Julieann Vose; Adesola Odunayo; Joshua M Price; Maggie Daves; Julie C Schildt; M Katherine Tolbert
Journal:  PeerJ       Date:  2019-05-31       Impact factor: 2.984

Review 5.  Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults.

Authors:  Eduardo López-Briz; Vicente Ruiz Garcia; Juan B Cabello; Sylvia Bort-Martí; Rafael Carbonell Sanchis; Amanda Burls
Journal:  Cochrane Database Syst Rev       Date:  2018-07-30
  5 in total

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