| Literature DB >> 10103215 |
I Wiid1, E Hoal-van Helden, D Hon, C Lombard, P van Helden.
Abstract
The limited number of effective antituberculosis drugs available necessitates optimizing current treatments. We show that melatonin, which is synthesized in the pineal gland, can cause at least a threefold increase in the efficacy of isoniazid. This suggests that tuberculosis chemotherapy can be improved by innate molecules such as melatonin.Entities:
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Year: 1999 PMID： 10103215 PMCID： PMC89241 DOI： 10.1128/AAC.43.4.975
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191