Literature DB >> 10103028

The structure of the carbohydrate backbone of the core-lipid A region of the lipopolysaccharide from a clinical isolate of Yersinia enterocolitica O:9.

S Müller-Loennies1, S Rund, E Ervelä, M Skurnik, O Holst.   

Abstract

Yersinia enterocolitica O:9 strain Ruokola/71-c-PhiR1-37-R possesses mainly rough-type lipopolysaccaride (LPS) and smaller amounts of S-form LPS. Structural analysis of the former is reported here. After deacylation of the LPS, the phosphorylated carbohydrate backbone of the inner core-lipid A region could be isolated by using high-performance anion-exchange chromatography. Its structure was determined by means of compositional and methylation analyses and 1H-, 13C-, and 31P-NMR spectroscopy as: [see text] in which L-alpha-D-Hep is L-glycero-alpha-D-manno-heptopyranose, D-alpha-D-Hep is D-glycero-alpha-D-manno-heptopyranose, and Kdo is 3-deoxy-D-manno-oct-2-ulopyranosonic acid. All hexoses are pyranoses.

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Year:  1999        PMID： 10103028     DOI： 10.1046/j.1432-1327.1999.00243.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN： 0014-2956


  5 in total

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5.  Regulatory protein OmpR influences the serum resistance of Yersinia enterocolitica O:9 by modifying the structure of the outer membrane.

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Journal:  PLoS One       Date:  2013-11-19       Impact factor: 3.240
  5 in total

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