| Literature DB >> 10102816 |
M C Timmermans1, A Hudson, P W Becraft, T Nelson.
Abstract
The regulation of members of the knotted1-like homeobox (knox) gene family is required for the normal initiation and development of lateral organs. The maize rough sheath2 (rs2) gene, which encodes a Myb-domain protein, is expressed in lateral organ primordia and their initials. Mutations in the rs2 gene permit ectopic expression of knox genes in leaf and floral primordia, causing a variety of developmental defects. Ectopic KNOX protein accumulation in rs2 mutants occurs in a subset of the normal rs2-expressing cells. This variegated accumulation of KNOX proteins in rs2 mutants suggests that rs2 represses knox expression through epigenetic means.Entities:
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Year: 1999 PMID: 10102816 DOI: 10.1126/science.284.5411.151
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728