Literature DB >> 10101855

An in vitro study on the toxic effects of nonylphenols (NP) in mitochondria.

M Bragadin1, G Perin, A Iero, S Manente, V Rizzoli, G Scutari.   

Abstract

This paper is focused on alkylphenols, compounds which are formed by the biodegradation of polyethoxilatedalkylphenols detergents. Our experiments show that alkylphenols act not only as detergents, but also as uncouplers of the oxidative phosphorylation. This effect, can be observed at very low doses, thus suggesting that the preferential target of nonylphenols in living organisms are mitochondria.

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Year:  1999        PMID: 10101855     DOI: 10.1016/s0045-6535(98)00412-3

Source DB:  PubMed          Journal:  Chemosphere        ISSN: 0045-6535            Impact factor:   7.086


  2 in total

1.  Effect of freeze-thaw cycles and 4-nonylphenol on cellular energy allocation in the freeze-tolerant enchytraeid Enchytraeus albidus.

Authors:  Ana L Patrício-Silva; Mónica J B Amorim
Journal:  Environ Sci Pollut Res Int       Date:  2015-10-21       Impact factor: 4.223

2.  Alkylphenolic compounds and their effect on the injury rate, survival and acetylcholinesterase activity of the rat neuronal cell line PC12.

Authors:  T P Talorete; H Isoda; T Maekawa
Journal:  Cytotechnology       Date:  2001-07       Impact factor: 2.058

  2 in total

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