| Literature DB >> 10100608 |
D P Kharakoz1, R S Khusainova, A V Gorelov, K A Dawson.
Abstract
DNA-DPPC complexes can be prepared by means of a single step procedure of mixing DNA solution and aqueous lipid dispersion in the presence of calcium ions. Interaction between DPPC and DNA brings about a biphasic shape of melting curves corresponding to the free lipid and the strongly bound one. The amount of the strongly bound lipid is 5 molecules per nucleotide which is close to the size of the first lipid monolayer around DNA molecule.Entities:
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Year: 1999 PMID: 10100608 DOI: 10.1016/s0014-5793(99)00165-9
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124