Literature DB >> 10100608

Stoichiometry of dipalmitoylphosphatidylcholine-DNA interaction in the presence of Ca2+: a temperature-scanning ultrasonic study.

D P Kharakoz1, R S Khusainova, A V Gorelov, K A Dawson.   

Abstract

DNA-DPPC complexes can be prepared by means of a single step procedure of mixing DNA solution and aqueous lipid dispersion in the presence of calcium ions. Interaction between DPPC and DNA brings about a biphasic shape of melting curves corresponding to the free lipid and the strongly bound one. The amount of the strongly bound lipid is 5 molecules per nucleotide which is close to the size of the first lipid monolayer around DNA molecule.

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Year:  1999        PMID: 10100608     DOI: 10.1016/s0014-5793(99)00165-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  3 in total

1.  Triple complexes of metal (II) cations with nucleic acids and phospholipid vesicles: the role of physiological cations (II).

Authors:  R I Zhdanov; A S Shmyrina; A R Zhdanov; A S Krylov; P Bruni
Journal:  Dokl Biochem Biophys       Date:  2005 Nov-Dec       Impact factor: 0.788

2.  The structural diversity of DNA-neutral phospholipids-divalent metal cations aggregates: a small-angle synchrotron X-ray diffraction study.

Authors:  Daniela Uhríková; Adrián Lengyel; Mária Hanulová; Sérgio S Funari; Pavol Balgavý
Journal:  Eur Biophys J       Date:  2006-07-25       Impact factor: 2.095

3.  Lipid membranes modulate the activity of RNA through sequence-dependent interactions.

Authors:  Tomasz Czerniak; James P Saenz
Journal:  Proc Natl Acad Sci U S A       Date:  2022-01-25       Impact factor: 11.205

  3 in total

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