Literature DB >> 1009674

A radioimmunoassay for growth hormone release-inhibiting hormone: method and quantitative tissue distribution.

S Kronheim, M Berelowitz, B L Pimstone.   

Abstract

A specific antiserum has been produced to haemocyanin conjugaed synthetic growth hormone release inhibiting hormone (GHRIH). This has allowed the development of a radioimmunoassay for GHRIH sensitive to 5 pg/tube. GHRIH content in 2 m acetic acid extracts of rat tissues have been measured and show the majority to be CNS-especially hypothalamus and septum and preoptic areas with substantial amounts in spinal cord and thalamus. Extra neurological localization in pancreas, gastric antrum, colon and thyroid have been demonstrated.

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Year:  1976        PMID： 1009674     DOI： 10.1111/j.1365-2265.1976.tb03865.x

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN： 0300-0664            Impact factor:   3.478


  17 in total

1.  High K+-induced release of somatostatin from the cortical preparation of rat brain.

Authors:  S L Lee; V Havlicek; A E Panerai; H G Friesen
Journal:  Experientia       Date:  1979-03-15

2.  Characterization of immunoreactive somatostatin released from rat nervous system in vitro.

Authors:  M C Sheppard; S Hendricks; A Hudson; S R Kronheim
Journal:  Biochem J       Date:  1982-02-01       Impact factor: 3.857

3.  Evidence for a role of free fatty acids in the regulation of somatostatin secretion in normal and alloxan diabetic dogs.

Authors:  T Wasada; B Howard; R E Dobbs; R H Unger
Journal:  J Clin Invest       Date:  1980-09       Impact factor: 14.808

4.  Cerebrospinal Fluid-Contacting Neurons Sense pH Changes and Motion in the Hypothalamus.

Authors:  Elham Jalalvand; Brita Robertson; Hervé Tostivint; Peter Löw; Peter Wallén; Sten Grillner
Journal:  J Neurosci       Date:  2018-07-23       Impact factor: 6.167

5.  Release of somatostatin-like immunoreactivity from incubated rat hypothalamus and cerebral cortex. Effects of glucose and glucoregulatory hormones.

Authors:  M Berelowitz; D Dudlak; L A Frohman
Journal:  J Clin Invest       Date:  1982-06       Impact factor: 14.808

6.  Release of somatostatin-like immunoreactivity from the perfused canine thyroid. Selective stimulatory effect of calcium ions.

Authors:  P Laurberg; H Orskov
Journal:  J Clin Invest       Date:  1981-05       Impact factor: 14.808

7.  Plasma somatostatin-like immunoreactivity during the interdigestive period in the dog.

Authors:  I Aizawa; Z Itoh; V Harris; R H Unger
Journal:  J Clin Invest       Date:  1981-07       Impact factor: 14.808

8.  Properties of endogenous somatostatin-like immunoreactivity and synthetic somatostatin in dog plasma.

Authors:  J M Conlon; C B Srikant; E Ipp; V Schusdziarra; W Vale; R H Unger
Journal:  J Clin Invest       Date:  1978-12       Impact factor: 14.808

9.  Somatostatin-like immunoreactivity in rat blood. Characterization, regional differences, and responses to oral and intravenous glucose.

Authors:  M Berelowitz; S Kronheim; B Pimstone; B Shapiro
Journal:  J Clin Invest       Date:  1978-05       Impact factor: 14.808

10.  Pancreatic and gastric somatostatin release in response to intragastric and intraduodenal nutrients and HCl in the dog.

Authors:  V Schusdziarra; V Harris; J M Conlon; A Arimura; R Unger
Journal:  J Clin Invest       Date:  1978-09       Impact factor: 14.808
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