N Husseinzadeh1, C Recinto. 1. Division of Gynecologic Oncology, University of Cincinnati College of Medicine, Cincinnati, Ohio, 45267-0526, USA.
Abstract
OBJECTIVE: The aim of this study was to determine the frequency of invasive cancer found from specimens removed by surgical excision on patients with diagnosis of VIN 3. METHODS: Seventy-eight patients with biopsy-proven vulvar intraepithelial neoplasia 3 (VIN 3) were treated by surgical excision. RESULTS: Sixteen patients (20.5%) were found to have invasion in the excised surgical specimen. Superficial invasion was seen in 7 patients (9%), 9 were noted to have >1 mm invasion (11.5%), and 1 patient had in situ Paget's disease (1.3%). CONCLUSION: Surgical excision should be considered a preferable method in management of patients with VIN 3. Copyright 1999 Academic Press.
OBJECTIVE: The aim of this study was to determine the frequency of invasive cancer found from specimens removed by surgical excision on patients with diagnosis of VIN 3. METHODS: Seventy-eight patients with biopsy-proven vulvar intraepithelial neoplasia 3 (VIN 3) were treated by surgical excision. RESULTS: Sixteen patients (20.5%) were found to have invasion in the excised surgical specimen. Superficial invasion was seen in 7 patients (9%), 9 were noted to have >1 mm invasion (11.5%), and 1 patient had in situ Paget's disease (1.3%). CONCLUSION: Surgical excision should be considered a preferable method in management of patients with VIN 3. Copyright 1999 Academic Press.
Authors: Mario Preti; Sarah Igidbashian; Silvano Costa; Paolo Cristoforoni; Luciano Mariani; Massimo Origoni; Maria T Sandri; Sara Boveri; Noemi Spolti; Laura Spinaci; Francesca Sanvito; Eleonora P Preti; Adriana Falasca; Gianluigi Radici; Leonardo Micheletti Journal: Ecancermedicalscience Date: 2015-04-29