Literature DB >> 10094715

Characterization of mdcR, a regulatory gene of the malonate catabolic system in Klebsiella pneumoniae.

H L Peng1, S R Shiou, H Y Chang.   

Abstract

The Klebsiella pneumoniae mdcR gene, which encodes a LysR-type regulator, was overexpressed in Escherichia coli. Purified MdcR was found to bind specifically to the control region of either the malonate decarboxylase (mdc) genes or mdcR. We have also demonstrated that MdcR is an activator of the expression of the mdc genes, whereas it represses the transcription of the putative control region of mdcR, PmdcR, indicating a negative autoregulatory control.

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Year:  1999        PMID: 10094715      PMCID: PMC93650     

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  20 in total

1.  Mutations in GltC that increase Bacillus subtilis gltA expression.

Authors:  B R Belitsky; A L Sonenshein
Journal:  J Bacteriol       Date:  1995-10       Impact factor: 3.490

2.  Sites required for GltC-dependent regulation of Bacillus subtilis glutamate synthase expression.

Authors:  B R Belitsky; P J Janssen; A L Sonenshein
Journal:  J Bacteriol       Date:  1995-10       Impact factor: 3.490

3.  The sixty nucleotide OccR operator contains a subsite essential and sufficient for OccR binding and a second subsite required for ligand-responsive DNA bending.

Authors:  L Wang; S C Winans
Journal:  J Mol Biol       Date:  1995-11-10       Impact factor: 5.469

4.  Long-range interaction between two promoters: activation of the leu-500 promoter by a distant upstream promoter.

Authors:  H Y Wu; J Tan; M Fang
Journal:  Cell       Date:  1995-08-11       Impact factor: 41.582

5.  Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for DNA binding and multimerization.

Authors:  I Kullik; J Stevens; M B Toledano; G Storz
Journal:  J Bacteriol       Date:  1995-03       Impact factor: 3.490

6.  Critical nucleotides in the interaction of a LysR-type regulator with its target promoter region. catBC promoter activation by CatR.

Authors:  M R Parsek; R W Ye; P Pun; A M Chakrabarty
Journal:  J Biol Chem       Date:  1994-04-15       Impact factor: 5.157

7.  Malonate decarboxylase of Malonomonas rubra, a novel type of biotin-containing acetyl enzyme.

Authors:  H Hilbi; I Dehning; B Schink; P Dimroth
Journal:  Eur J Biochem       Date:  1992-07-01

8.  Differential DNA bending introduced by the Pseudomonas putida LysR-type regulator, CatR, at the plasmid-borne pheBA and chromosomal catBC promoters.

Authors:  M R Parsek; M Kivisaar; A M Chakrabarty
Journal:  Mol Microbiol       Date:  1995-03       Impact factor: 3.501

9.  Purification and properties of a novel type of malonate decarboxylase from Acinetobacter calcoaceticus.

Authors:  Y S Kim; H S Byun
Journal:  J Biol Chem       Date:  1994-11-25       Impact factor: 5.157

10.  Circadian rhythms in prokaryotes: luciferase as a reporter of circadian gene expression in cyanobacteria.

Authors:  T Kondo; C A Strayer; R D Kulkarni; W Taylor; M Ishiura; S S Golden; C H Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-15       Impact factor: 11.205

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  5 in total

1.  Malonate degradation in Acinetobacter baylyi ADP1: operon organization and regulation by MdcR.

Authors:  Julie L Stoudenmire; Alicia L Schmidt; Melissa P Tumen-Velasquez; Kathryn T Elliott; Nicole S Laniohan; S Walker Whitley; Nickolaus R Galloway; Melesse Nune; Michael West; Cory Momany; Ellen L Neidle; Anna C Karls
Journal:  Microbiology       Date:  2017-05       Impact factor: 2.777

2.  The malonate decarboxylase operon of Acinetobacter calcoaceticus KCCM 40902 is regulated by malonate and the transcriptional repressor MdcY.

Authors:  J H Koo; I H Cho; Y S Kim
Journal:  J Bacteriol       Date:  2000-11       Impact factor: 3.490

3.  Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast.

Authors:  Mette L Skjoedt; Tim Snoek; Kanchana R Kildegaard; Dushica Arsovska; Michael Eichenberger; Tobias J Goedecke; Arun S Rajkumar; Jie Zhang; Mette Kristensen; Beata J Lehka; Solvej Siedler; Irina Borodina; Michael K Jensen; Jay D Keasling
Journal:  Nat Chem Biol       Date:  2016-09-19       Impact factor: 15.040

4.  Regulation and evolution of malonate and propionate catabolism in proteobacteria.

Authors:  I A Suvorova; D A Ravcheev; M S Gelfand
Journal:  J Bacteriol       Date:  2012-04-13       Impact factor: 3.490

5.  A Disjointed Pathway for Malonate Degradation by Rhodopseudomonas palustris.

Authors:  Zhaobao Wang; Qifeng Wen; Caroline S Harwood; Bo Liang; Jianming Yang
Journal:  Appl Environ Microbiol       Date:  2020-05-19       Impact factor: 4.792

  5 in total

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