| Literature DB >> 10093806 |
S Lopez-Sastre1, J M Gonzalo-Orden, J A Altónaga, J R Altónaga, M A Orden.
Abstract
This study compares the osteointegration of titanium implants coated with bioglass (Biovetro GSB formula) and with hydroxyapatite (HAP). Twenty-four bioglass-coated and 24 HAP-coated cylinders were implanted in the femoral diaphyses of sheep, and examined after 2, 4, 6, 8, 12, and 16 weeks. The HAP coating gave a stronger and earlier fixation to the bone than did bioglass. Bioglass formed a tissue interface which showed a macrophage reaction with little new bone formation activity. In contrast, HPA, showed intense new bone formation, with highly mineralised osseous trabeculae in the neighbourhood of the interface.Entities:
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Year: 1998 PMID： 10093806 PMCID： PMC3619677 DOI： 10.1007/s002640050282
Source DB: PubMed Journal: Int Orthop ISSN： 0341-2695 Impact factor: 3.075