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Literature DB >> 1008996

Experimental canine distemper infection as a means of demonstrating latent effects of subacute lead intoxication.

Abstract

Observations on the response of the body to experimental infection with distemper virus in dogs previously dosed subacutely with lead have demonstrated a latent effect of lead on several body systems. Effects which indicated a relationship to earlier treatment with lead included evidence for stimulation of haemoglobin synthesis, changes to red blood cells resulting in increased destruction, increased vulnerability of the parenchymatous cells of the liver to damage, reduction in the weight of the skeleton and thyroid, an increase in weight of the thymus and brain and histopathological changes in the thymus.

Entities: Disease Species

Mesh：

Year: 1976 PMID： 1008996 PMCID： PMC2041248

Source DB: PubMed Journal: Br J Exp Pathol ISSN： 0007-1021

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References

16 in total

1. AUTOMATED AND MANUAL DIRECT METHODS FOR THE DETERMINATION OF BLOOD UREA.

Authors: W H MARSH; B FINGERHUT; H MILLER
Journal: Clin Chem Date: 1965-06 Impact factor: 8.327

2. Revised spectrophotometric methods for the determination of glutamic-oxalacetic transaminase, glutamic-pyruvic transaminase, and lactic acid dehydrogenase.

Authors: R J HENRY; N CHIAMORI; O J GOLUB; S BERKMAN
Journal: Tech Bull Regist Med Technol Date: 1960-09

9. The influence of experimental distemper infection on the distribution of lead in dogs previously subacutely intoxicated with lead carbonate.

Authors: D J White; A J Marshall; S McLeod
Journal: Br J Exp Pathol Date: 1975-12

10. Electron microscopic and chemical studies of the vascular changes and edema of lead encephalopathy. A comparative study of the human and experimental disease.

Authors: R A Clasen; J F Hartmann; A J Starr; P S Coogan; S Pandolfi; I Laing; R Becker; G M Hass
Journal: Am J Pathol Date: 1974-02 Impact factor: 4.307

Experimental canine distemper infection as a means of demonstrating latent effects of subacute lead intoxication.

1. AUTOMATED AND MANUAL DIRECT METHODS FOR THE DETERMINATION OF BLOOD UREA.

2. Revised spectrophotometric methods for the determination of glutamic-oxalacetic transaminase, glutamic-pyruvic transaminase, and lactic acid dehydrogenase.

3. Lead poisoning in children; correlation of clinical and pathological findings.

4. Reticuloendothelial and hepatic functional alterations following lead acetate administration.

5. Enzyme inhibition by lead under normal urban conditions.

6. Studies with an attenuated canine distemper vaccine derived from chick embryo cultures.

7. Ultrastructural changes in the liver of baboons following lead and endotoxin administration.

8. Involution of the human thymus.

9. The influence of experimental distemper infection on the distribution of lead in dogs previously subacutely intoxicated with lead carbonate.

10. Electron microscopic and chemical studies of the vascular changes and edema of lead encephalopathy. A comparative study of the human and experimental disease.