L C Dierker1, K R Merikangas, P Szatmari. 1. Wesleyan University, Department of Psychology, Middletown, CT 06459, USA. ldierker@wesleyan.edu
Abstract
OBJECTIVE: To examine the influence of parental mating types for substance abuse and anxiety/affective disorders on the risk of psychopathology among child and adolescent offspring. METHOD: Emotional and behavioral disorders were assessed in offspring, aged 7 to 17 years, of male and female parents who served as probands from a family study of comorbidity of substance abuse and anxiety disorders. RESULTS: The findings indicated that (1) patterns of psychopathology among offspring were similar for mothers and fathers; (2) spouse concordance for psychopathology was greater among parents with substance abuse than among those with anxiety, particularly among female substance abusers; (3) there was a direct relationship between the number of affected parents and the magnitude of psychopathology in children, particularly with respect to the anxiety disorders; and (4) by contrast, rates of conduct disorder were elevated only among offspring of dually affected parents, irrespective of the specific parental disorders. CONCLUSIONS: These findings underscore the importance of the contribution of both mothers and fathers, particularly those with concordance for psychiatric disorders, to the development of psychopathology in offspring.
OBJECTIVE: To examine the influence of parental mating types for substance abuse and anxiety/affective disorders on the risk of psychopathology among child and adolescent offspring. METHOD: Emotional and behavioral disorders were assessed in offspring, aged 7 to 17 years, of male and female parents who served as probands from a family study of comorbidity of substance abuse and anxiety disorders. RESULTS: The findings indicated that (1) patterns of psychopathology among offspring were similar for mothers and fathers; (2) spouse concordance for psychopathology was greater among parents with substance abuse than among those with anxiety, particularly among female substance abusers; (3) there was a direct relationship between the number of affected parents and the magnitude of psychopathology in children, particularly with respect to the anxiety disorders; and (4) by contrast, rates of conduct disorder were elevated only among offspring of dually affected parents, irrespective of the specific parental disorders. CONCLUSIONS: These findings underscore the importance of the contribution of both mothers and fathers, particularly those with concordance for psychiatric disorders, to the development of psychopathology in offspring.
Authors: Katie A McLaughlin; Anne M Gadermann; Irving Hwang; Nancy A Sampson; Ali Al-Hamzawi; Laura Helena Andrade; Matthias C Angermeyer; Corina Benjet; Evelyn J Bromet; Ronny Bruffaerts; José Miguel Caldas-de-Almeida; Giovanni de Girolamo; Ron de Graaf; Silvia Florescu; Oye Gureje; Josep Maria Haro; Hristo Ruskov Hinkov; Itsuko Horiguchi; Chiyi Hu; Aimee Nasser Karam; Viviane Kovess-Masfety; Sing Lee; Samuel D Murphy; S Haque Nizamie; José Posada-Villa; David R Williams; Ronald C Kessler Journal: Br J Psychiatry Date: 2012-03-08 Impact factor: 9.319
Authors: Laila F M Contractor; Karen L Celedonia; Mario Cruz; Antoine Douaihy; Jane N Kogan; Robert Marin; Bradley D Stein Journal: Community Ment Health J Date: 2010-11-24
Authors: Sami Pirkola; Erkki Isometsä; Hillevi Aro; Laura Kestilä; Juha Hämäläinen; Juha Veijola; Olli Kiviruusu; Jouko Lönnqvist Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2005-10-07 Impact factor: 4.328
Authors: R J Brooker; K M Alto; K Marceau; R Najjar; L D Leve; J M Ganiban; D S Shaw; D Reiss; J M Neiderhiser Journal: J Dev Orig Health Dis Date: 2016-08-30 Impact factor: 2.401
Authors: Anne Buu; Cydney Dipiazza; Jing Wang; Leon I Puttler; Hiram E Fitzgerald; Robert A Zucker Journal: J Stud Alcohol Drugs Date: 2009-07 Impact factor: 2.582