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Literature DB >> 10087405

The human immunoglobulin heavy variable genes.

N Pallarès¹, S Lefebvre, V Contet, F Matsuda, M P Lefranc.

Abstract

'Human Immunoglobulin Heavy Variable Genes', the fourth report of the 'IMGT Locus on Focus' section, comprises five tables entitled: (1) 'Number of human germline IGHV genes at 14q32.33 and potential repertoire'; (2) 'Human germline IGHV genes at 14q32.33'; (3) 'Human IGHV orphons on chromosome 15 (15q11.2)'; (4) 'Human IGHV orphons on chromosome 16 (16p11.2)', and (5) 'Human IGHV allele table'. These tables are available at the IMGT Marie-Paule page from IMGT, the international ImMunoGeneTics database (http://imgt.cnusc.fr:8104) created by Marie-Paule Lefranc, Université Montpellier II, CNRS, France.

Entities: Gene Species

Mesh：

Substances：

Year: 1999 PMID： 10087405 DOI： 10.1159/000019095

Source DB: PubMed Journal: Exp Clin Immunogenet ISSN： 0254-9670

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Cited

19 in total

1. Combinatorial library cloning of human antibodies to Streptococcus pneumoniae capsular polysaccharides: variable region primary structures and evidence for somatic mutation of Fab fragments specific for capsular serotypes 6B, 14, and 23F.

Authors: A H Lucas; K D Moulton; V R Tang; D C Reason
Journal: Infect Immun Date: 2001-02 Impact factor: 3.441

2. IMGT, the international ImMunoGeneTics database.

Authors: M Ruiz; V Giudicelli; C Ginestoux; P Stoehr; J Robinson; J Bodmer; S G Marsh; R Bontrop; M Lemaitre; G Lefranc; D Chaume; M P Lefranc
Journal: Nucleic Acids Res Date: 2000-01-01 Impact factor: 16.971

Review 3. Human gamma delta T cells: Evolution and ligand recognition.

Authors: Erin J Adams; Siyi Gu; Adrienne M Luoma
Journal: Cell Immunol Date: 2015-05-06 Impact factor: 4.868

4. Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation.

Authors: Corey T Watson; Karyn M Steinberg; John Huddleston; Rene L Warren; Maika Malig; Jacqueline Schein; A Jeremy Willsey; Jeffrey B Joy; Jamie K Scott; Tina A Graves; Richard K Wilson; Robert A Holt; Evan E Eichler; Felix Breden
Journal: Am J Hum Genet Date: 2013-03-28 Impact factor: 11.025

5. Genomic screening by 454 pyrosequencing identifies a new human IGHV gene and sixteen other new IGHV allelic variants.

Authors: Yan Wang; Katherine J Jackson; Bruno Gäeta; William Pomat; Peter Siba; William A Sewell; Andrew M Collins
Journal: Immunogenetics Date: 2011-01-20 Impact factor: 2.846

6. IGH V3-2301 and its allele V3-2303 differ in their capacity to form the canonical human antibody combining site specific for the capsular polysaccharide of Haemophilus influenzae type b.

Authors: Leyu Liu; Alexander H Lucas
Journal: Immunogenetics Date: 2003-07-04 Impact factor: 2.846

The human immunoglobulin heavy variable genes.

1. Combinatorial library cloning of human antibodies to Streptococcus pneumoniae capsular polysaccharides: variable region primary structures and evidence for somatic mutation of Fab fragments specific for capsular serotypes 6B, 14, and 23F.

2. IMGT, the international ImMunoGeneTics database.

Review 3. Human gamma delta T cells: Evolution and ligand recognition.

4. Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation.

5. Genomic screening by 454 pyrosequencing identifies a new human IGHV gene and sixteen other new IGHV allelic variants.

6. IGH V3-2301 and its allele V3-2303 differ in their capacity to form the canonical human antibody combining site specific for the capsular polysaccharide of Haemophilus influenzae type b.

7. The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β.

8. The reported germline repertoire of human immunoglobulin kappa chain genes is relatively complete and accurate.

9. Tracing antigen signatures in the human IgE repertoire.

Review 10. Immunoglobulin germline gene variation and its impact on human disease.