| Literature DB >> 10085048 |
S S Way1, A C Borczuk, M B Goldberg.
Abstract
Shigella flexneri cydC, which is deficient in cytochrome bd, was rapidly cleared from the lungs of intranasally inoculated mice and was Sereny negative, yet it induced 93% protection against challenge with wild-type S. flexneri. Mice that lack immunoglobulin A (IgA) were fully protected, suggesting that IgA may not be required for adaptive immunity in this model system.Entities:
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Year: 1999 PMID: 10085048 PMCID: PMC96558 DOI: 10.1128/IAI.67.4.2001-2004.1999
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441