RATIONALE AND OBJECTIVE: The purpose of this prospective, double-blind study was to correlate motor functional MRI (fMRI) with cortical brain mapping by intraoperative stimulation using 3D reconstructed images of the surface of the brain, and to validate the spatial data of fMRI in patients with brain tumors. METHODS: Fourteen patients with tumors of the rolandic region underwent functional MR mapping of the hand region and subsequently cortical mapping before tumor resection. Data obtained with fMRI and brain mapping were not known previously by the neurosurgeon and by the neuroradiologist, respectively (double-blind study). RESULTS: In each case, the results of direct cortical mapping matched those obtained with fMRI, both positively and negatively, although the extent of the functional activations was larger than the area required to elicit the corresponding movement during intraoperative brain mapping. CONCLUSION: fMRI can be used before surgery to assess motor functional area in patients with rolandic tumors. More studies are needed to validate during surgery the real extent of fMRI activations.
RATIONALE AND OBJECTIVE: The purpose of this prospective, double-blind study was to correlate motor functional MRI (fMRI) with cortical brain mapping by intraoperative stimulation using 3D reconstructed images of the surface of the brain, and to validate the spatial data of fMRI in patients with brain tumors. METHODS: Fourteen patients with tumors of the rolandic region underwent functional MR mapping of the hand region and subsequently cortical mapping before tumor resection. Data obtained with fMRI and brain mapping were not known previously by the neurosurgeon and by the neuroradiologist, respectively (double-blind study). RESULTS: In each case, the results of direct cortical mapping matched those obtained with fMRI, both positively and negatively, although the extent of the functional activations was larger than the area required to elicit the corresponding movement during intraoperative brain mapping. CONCLUSION: fMRI can be used before surgery to assess motor functional area in patients with rolandic tumors. More studies are needed to validate during surgery the real extent of fMRI activations.
Authors: Jackson D Hamilton; Vinodh A Kumar; L Anne Hayman; Sujit S Prabhu; Ping Hou; Edward F Jackson; Megan Groneman; John Pagani; Mark Vabulas; Ashok J Kumar Journal: J Comput Assist Tomogr Date: 2012 Mar-Apr Impact factor: 1.826
Authors: Benoit Pirotte; Carine Neugroschl; Thierry Metens; David Wikler; Vincent Denolin; Philippe Voordecker; Alfred Joffroy; Nicolas Massager; Jacques Brotchi; Marc Levivier; Danielle Baleriaux Journal: AJNR Am J Neuroradiol Date: 2005-10 Impact factor: 3.825
Authors: E Mormina; M Longo; A Arrigo; C Alafaci; F Tomasello; A Calamuneri; S Marino; M Gaeta; S L Vinci; F Granata Journal: AJNR Am J Neuroradiol Date: 2015-06-25 Impact factor: 3.825
Authors: Zhixi Li; Kyung K Peck; Nicole P Brennan; Mehrnaz Jenabi; Meier Hsu; Zhigang Zhang; Andrei I Holodny; Robert J Young Journal: J Biomed Sci Eng Date: 2013-02