Literature DB >> 10083737

A novel human gene whose product shares significant homology with the bovine brain-specific protein p25 on chromosome 5p15.3.

N Seki1, A Hattori, S Sugano, Y Suzuki, A Nakagawara, M Muramatsu, T Hori, T Saito.   

Abstract

Here, we report on the sequence features and chromosomal location of a novel human gene which shares significant homology with the bovine brain-specific protein p25. Based on polymerase chain reaction analysis with a human/rodent monochromosomal hybrid cell panel and a radiation hybrid panel, the gene was mapped on to p15.3 region of chromosome 5.

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Year:  1999        PMID: 10083737     DOI: 10.1007/s100380050122

Source DB:  PubMed          Journal:  J Hum Genet        ISSN: 1434-5161            Impact factor:   3.172


  6 in total

Review 1.  Functional aspects of cellular microcompartmentation in the development of neurodegeneration: mutation induced aberrant protein-protein associations.

Authors:  Judit Ovádi; Ferenc Orosz; Susan Hollán
Journal:  Mol Cell Biochem       Date:  2004 Jan-Feb       Impact factor: 3.396

2.  p25alpha is flexible but natively folded and binds tubulin with oligomeric stoichiometry.

Authors:  Daniel E Otzen; Ditte M S Lundvig; Reinhard Wimmer; Lotte H Nielsen; Jakob R Pedersen; Poul H Jensen
Journal:  Protein Sci       Date:  2005-05-09       Impact factor: 6.725

3.  Stable knockdown of TPPP3 by RNA interference in Lewis lung carcinoma cell inhibits tumor growth and metastasis.

Authors:  Wenbai Zhou; Jiada Li; Xuanchun Wang; Renming Hu
Journal:  Mol Cell Biochem       Date:  2010-06-23       Impact factor: 3.396

4.  Depletion of tubulin polymerization promoting protein family member 3 suppresses HeLa cell proliferation.

Authors:  Wenbai Zhou; Xuanchun Wang; Lianxi Li; Xiaocheng Feng; Zhihong Yang; Weiwei Zhang; Renming Hu
Journal:  Mol Cell Biochem       Date:  2009-07-25       Impact factor: 3.396

5.  TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation.

Authors:  L Tirián; E Hlavanda; J Oláh; I Horváth; F Orosz; B Szabó; J Kovács; J Szabad; J Ovádi
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-17       Impact factor: 11.205

6.  Molecular interaction of TPPP with PrP antagonized the CytoPrP-induced disruption of microtubule structures and cytotoxicity.

Authors:  Rui-Min Zhou; Yuan-Yuan Jing; Yan Guo; Chen Gao; Bao-Yun Zhang; Cao Chen; Qi Shi; Chan Tian; Zhao-Yun Wang; Han-Shi Gong; Jun Han; Bian-Li Xu; Xiao-Ping Dong
Journal:  PLoS One       Date:  2011-08-12       Impact factor: 3.240

  6 in total

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