Literature DB >> 10082218

[D-Ala2, D-Leu5]enkephalin blocks the methamphetamine-induced c-fos mRNA increase in mouse striatum.

T Hayashi1, L I Tsao, J L Cadet, T P Su.   

Abstract

The administration of methamphetamine caused an increase of c-fos mRNA in the striatum of the mouse. A systemic injection of the delta-opioid receptor agonist, [D-Ala2, D-Leu5]enkephalin (DADLE), attenuated the c-fos mRNA increase induced by methamphetamine. These results suggest that endogenous delta-opioid peptides might counteract certain genomic influences exerted by psychostimulants such as methamphetamine.

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Year:  1999        PMID: 10082218     DOI: 10.1016/s0014-2999(98)00947-9

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  2 in total

1.  Hibernation-like state induced by an opioid peptide protects against experimental stroke.

Authors:  Cesar V Borlongan; Teruo Hayashi; Peter R Oeltgen; Tsung-Ping Su; Yun Wang
Journal:  BMC Biol       Date:  2009-06-17       Impact factor: 7.431

2.  Delta opioid receptor and its peptide: a receptor-ligand neuroprotection.

Authors:  Meaghan Staples; Sandra Acosta; Naoki Tajiri; Mibel Pabon; Yuji Kaneko; Cesar V Borlongan
Journal:  Int J Mol Sci       Date:  2013-08-23       Impact factor: 5.923

  2 in total

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