Literature DB >> 10081819

Synthesis and antituberculosis activity of some new 2-quinoxalinecarbonitriles.

M E Montoya1, Y Sainz, M A Ortega, A Lopez De Cerain, A Monge.   

Abstract

Tuberculosis, an ancient disease undergoing recent control by public hygiene and drug therapy, has experienced a recrudescence throughout the world. New and effective therapies are rapidly needed to combat infections caused by these strains. Some new 2-quinoxalinecarbonitriles have been synthesized and tested as antituberculosis agents and interesting results have been obtained from the first screening.

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Year:  1998        PMID： 10081819     DOI： 10.1016/s0014-827x(98)00067-6

Source DB:  PubMed          Journal:  Farmaco        ISSN： 0014-827X


  7 in total

1.  Efficacy of quinoxaline-2-carboxylate 1,4-di-N-oxide derivatives in experimental tuberculosis.

Authors:  Esther Vicente; Raquel Villar; Asunción Burguete; Beatriz Solano; Silvia Pérez-Silanes; Ignacio Aldana; Joseph A Maddry; Anne J Lenaerts; Scott G Franzblau; Sang-Hyun Cho; Antonio Monge; Robert C Goldman
Journal:  Antimicrob Agents Chemother       Date:  2008-07-14       Impact factor: 5.191

2.  Fused heterocycles: synthesis of some new imidazo[1,2-a]- pyridine derivatives.

Authors:  Birgul Ozden Kasimogullari; Zafer Cesur
Journal:  Molecules       Date:  2004-09-30       Impact factor: 4.411

3.  In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide.

Authors:  Raquel Villar; Esther Vicente; Beatriz Solano; Silvia Pérez-Silanes; Ignacio Aldana; Joseph A Maddry; Anne J Lenaerts; Scott G Franzblau; Sang-Hyun Cho; Antonio Monge; Robert C Goldman
Journal:  J Antimicrob Chemother       Date:  2008-05-23       Impact factor: 5.790

4.  Esters of Quinoxaline 1`4-Di-N-oxide with Cytotoxic Activity on Tumor Cell Lines Based on NCI-60 Panel.

Authors:  Gildardo Rivera; Syed Shoaib Ahmad Shah; Daniel Arrieta-Baez; Isidro Palos; Antonio Mongue; Luvia Enid Sánchez-Torres
Journal:  Iran J Pharm Res       Date:  2017       Impact factor: 1.696

5.  Synthesis and Characterization of Novel 2-Acyl-3-trifluoromethylquinoxaline 1,4-Dioxides as Potential Antimicrobial Agents.

Authors:  Galina I Buravchenko; Dmitry A Maslov; Md Shah Alam; Natalia E Grammatikova; Svetlana G Frolova; Aleksey A Vatlin; Xirong Tian; Ivan V Ivanov; Olga B Bekker; Maxim A Kryakvin; Olga A Dontsova; Valery N Danilenko; Tianyu Zhang; Andrey E Shchekotikhin
Journal:  Pharmaceuticals (Basel)       Date:  2022-01-27

Review 6.  Quinoxaline 1,4-di-N-Oxides: Biological Activities and Mechanisms of Actions.

Authors:  Guyue Cheng; Wei Sa; Chen Cao; Liangliang Guo; Haihong Hao; Zhenli Liu; Xu Wang; Zonghui Yuan
Journal:  Front Pharmacol       Date:  2016-03-21       Impact factor: 5.810

7.  Unexpected reduction of ethyl 3-phenylquinoxaline-2- carboxylate 1,4-di-N-oxide derivatives by amines.

Authors:  Lidia M Lima; Esther Vicente; Beatriz Solano; Silvia Pérez-Silanes; Ignacio Aldana; Antonio Monge
Journal:  Molecules       Date:  2008-01-17       Impact factor: 4.411
  7 in total

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