Literature DB >> 10081289

[Ciguatera poisoning. Growing differential diagnostic significance in the age of foreign tourism].

C Blume1, M Rapp, J Rath, H Köller, G Arendt, D Bach, B Grabensee.   

Abstract

BACKGROUND: In the tropic sea there are carnivore fishes, e.g. the "peak bass", that incorporate toxin producing seaweed and can cause the ciguatera intoxication. Due to the frequent tourism to tropic regions even more cases of ciguatera intoxication can be seen in Europe. The late phase of ciguatera intoxication has hardly been recognized due to its different unspecific symptoms. In some cases ciguatera intoxication can even grow a vital threatening. CASE DESCRIPTION: Four patients from a travel group addressed us 4 and 14 days after breaking off their holidays in the Dominican republic. They presented complex neurological symptoms including paraesthesia, nervousness, inverse temperature perception, muscle cramps, headache and dizziness. The physical and apparative investigation of the patients, whose age ranked between 22 and 31 years, was totally unobtrusive. Essential for the diagnosis of ciguatera intoxication was the clue to the symptom causing dinner at their holiday location existing of "peak bass and lemon sauce". First symptoms in all members of the travel group were diarrhea, sickness and sweating. In this late phase only a symptomatic therapy could be offered.
CONCLUSION: The here described cases show the importance of a comprehensive information for tropic travellers as for physicians accounted to in the acute phase of ciguatera intoxication, because recognized early enough (within the first 24 hours) the total symptomatology of ciguatera intoxication can be prevented effectively by intravenous infusions of mannitol.

Entities:  

Mesh:

Year:  1999        PMID: 10081289     DOI: 10.1007/bf03044694

Source DB:  PubMed          Journal:  Med Klin (Munich)        ISSN: 0723-5003


  13 in total

1.  Travel and ciguatera fish poisoning.

Authors:  W R Lange; F R Snyder; P J Fudala
Journal:  Arch Intern Med       Date:  1992-10

2.  Effects of ciguatoxin on current and voltage clamped frog myelinated nerve fibre.

Authors:  E Benoit; A M Legrand; J M Dubois
Journal:  Toxicon       Date:  1986       Impact factor: 3.033

3.  [Neurologic manifestations of ciguatera. 3 cases with a neurophysiologic study and examination of one nerve biopsy].

Authors:  J L Allsop; L Martini; H Lebris; J Pollard; J Walsh; S Hodgkinson
Journal:  Rev Neurol (Paris)       Date:  1986       Impact factor: 2.607

Review 4.  Ciguatera.

Authors:  A E Swift; T R Swift
Journal:  J Toxicol Clin Toxicol       Date:  1993

5.  Ciguatera and mannitol: experience with a new treatment regimen.

Authors:  J H Pearn; R J Lewis; T Ruff; M Tait; J Quinn; W Murtha; G King; A Mallett; N C Gillespie
Journal:  Med J Aust       Date:  1989-07-17       Impact factor: 7.738

6.  Clinical observations on 3,009 cases of ciguatera (fish poisoning) in the South Pacific.

Authors:  R Bagnis; T Kuberski; S Laugier
Journal:  Am J Trop Med Hyg       Date:  1979-11       Impact factor: 2.345

7.  Studies on the mode of action of ciguateric toxins.

Authors:  A M Legrand; M Galonnier; R Bagnis
Journal:  Toxicon       Date:  1982       Impact factor: 3.033

8.  Preliminary immunologic studies of ciguatera poisoning.

Authors:  D L Emerson; R M Galbraith; J P McMillan; T B Higerd
Journal:  Arch Intern Med       Date:  1983-10

9.  Treatment of ciguatera fish poisoning with amitriptyline and nifedipine.

Authors:  G M Calvert; D O Hryhorczuk; J B Leikin
Journal:  J Toxicol Clin Toxicol       Date:  1987

10.  Clinical features of ciguatera fish poisoning: a study of the disease in the US Virgin Islands.

Authors:  J G Morris; P Lewin; N T Hargrett; C W Smith; P A Blake; R Schneider
Journal:  Arch Intern Med       Date:  1982-06
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