| Literature DB >> 10081148 |
N M Gulaya1, A I Kuzmenko, V M Margitich, N M Govseeva, S D Melnichuk, T M Goridko, A D Zhukov.
Abstract
Two long-chain N-acylethanolamines (NAEs), N-palmitoyl- (NPE) and N-stearoylethanolamine (NSE), are shown to inhibit an in vitro non-enzymatic Fe(2+)-induced free radical oxidation of lipids in the liver mitochondria of rats with hypoxic hypoxia. NSE appeared to be more effective than NPE in suppressing some kinetic parameters of the Fe(2+)-induced chemiluminescence. The inhibitory action of NAEs on non-enzymatic lipid peroxidation supports the idea that they possess membrane protective properties.Entities:
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Year: 1998 PMID： 10081148 DOI： 10.1016/s0009-3084(98)00093-0
Source DB: PubMed Journal: Chem Phys Lipids ISSN： 0009-3084 Impact factor: 3.329