Literature DB >> 1008114

The effect of antibiotics on mortality from infectious diseases in Sweden and Finland.

E Hemminki, A Paakkulainen.   

Abstract

A study was carried out to determine whether the preexisting decline in mortality rates from infectious diseases accelerated after the introduction of antibiotic and chemotherapeutic drugs. Linear regression curves showed that in Sweden mortality rates declined faster in septicemia, syphilis, and non-memingococcal meningitis after the introduction of these drugs. By contrast, for the ten other infectious diseases studied, (scarlet fever, erysipelas, acute rheumatic fever, puerperal sepsis, meningococcal infection, bronchitis, pneumonia, tuberculosis, typhoid fever, and acute gastroenteritis) no such accelerated decline in mortality could be detected. The findings suggest that antibiotic and chemotherapeutic drugs have not had the dramatic effect of the mortality of infectious diseases popularly attributed to them.

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Year:  1976        PMID: 1008114      PMCID: PMC1653532          DOI: 10.2105/ajph.66.12.1180

Source DB:  PubMed          Journal:  Am J Public Health        ISSN: 0090-0036            Impact factor:   9.308


  4 in total

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Authors:  E B CHAIN
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2.  [Trends in tuberculosis mortality & morbidity in Finland & Helsinki during the period 1900-1956].

Authors:  A S HARO; J PATIALA
Journal:  Duodecim       Date:  1958

3.  Study on tuberculosis mortality in Sweden.

Authors:  T SHIMAO
Journal:  Acta Tuberc Scand       Date:  1956

4.  Health care experiment at Many Farms.

Authors:  W McDermott; K W Deuschle; C R Barnett
Journal:  Science       Date:  1972-01-07       Impact factor: 47.728

  4 in total
  6 in total

1.  Early antimicrobial therapy in severe sepsis and septic shock.

Authors:  Anand Kumar
Journal:  Curr Infect Dis Rep       Date:  2010-09       Impact factor: 3.725

2.  Puerperal fever, the streptococcus, and the sulphonamides, 1911-1945.

Authors:  I Loudon
Journal:  Br Med J (Clin Res Ed)       Date:  1987-08-22

3.  The contribution of medical measures to the decline of mortality from respiratory tuberculosis: an age-period-cohort model.

Authors:  J J Collins
Journal:  Demography       Date:  1982-08

4.  Decreasing trend in mortality of chronic myelogenous leukemia patients after introduction of imatinib in Japan and the U.S.

Authors:  Dai Chihara; Hidemi Ito; Tomohiro Matsuda; Kota Katanoda; Akiko Shibata; Kumiko Saika; Tomotaka Sobue; Keitaro Matsuo
Journal:  Oncologist       Date:  2012-09-12

5.  Trends in "avoidable" mortality in Sweden, 1974-1985.

Authors:  R Westerling
Journal:  J Epidemiol Community Health       Date:  1992-10       Impact factor: 3.710

Review 6.  An alternate pathophysiologic paradigm of sepsis and septic shock: implications for optimizing antimicrobial therapy.

Authors:  Anand Kumar
Journal:  Virulence       Date:  2013-11-01       Impact factor: 5.882

  6 in total

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