Literature DB >> 1008018

Smooth muscle sensitization induced by vinblastine.

J P Famaey, J Fontaine, J Reuse.   

Abstract

At the optimal concentration of 10 mg/l, vinblastine increases the submaximal contractions of the isolated guinea-pig ileum induced by the following agonists: acetylcholine, histamine, nicotine, angiotensine, prostaglandins E1 and F2alpha (but not serotonine). It also increases the contractions induced by transmural electrical stimulations of the guinea-pig ileum and reverses the inhibitory effect of non-steroidal anti-inflammatory drugs on these electrically-induced contractions.

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Year:  1976        PMID: 1008018     DOI: 10.1007/bf02026095

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  7 in total

1.  The response of the guineapig ileum to electrical stimulation by coaxial electrodes.

Authors:  W D PATON
Journal:  J Physiol       Date:  1955-02-28       Impact factor: 5.182

2.  The effects of prostaglandins on guinea-pig isolated intestine and their possible contribution to muscle activity and tone.

Authors:  A Bennett; K G Eley; H L Stockley
Journal:  Br J Pharmacol       Date:  1975-06       Impact factor: 8.739

3.  The action of dibutyryl cyclic GMP (N2-2'-O-dibutyryl cyclic guanosine-3',5'-mono-phosphate) on the ileum of guinea pig.

Authors:  I Takayanagi; K Takagi
Journal:  Jpn J Pharmacol       Date:  1973-08

4.  Decline of tissue noradrenaline under the influence of a mitotic inhibitor.

Authors:  P Keen; A Livingston
Journal:  Nature       Date:  1970-08-29       Impact factor: 49.962

5.  Vinblastine and vincristine: a study of their action on tissue concentrations of epinephrine, norephinephrine and acetylcholine.

Authors:  D L Cheney; I Hanin; R Massarelli; M Trabucchi; E Costa
Journal:  Neuropharmacology       Date:  1973-03       Impact factor: 5.250

6.  Interactions of tubulin with vinblastine and guanosine triphosphate.

Authors:  R W Berry; M L Shelanski
Journal:  J Mol Biol       Date:  1972-10-28       Impact factor: 5.469

7.  Inhibiting effects of morphine, chloroquine, nonsteroidal and steroidal anti-inflammatory drugs on electrically-induced contractions of guinea-pig ileum and the reversing effect of prostaglandins.

Authors:  J P Famaey; J Fontaine; J Reuse
Journal:  Agents Actions       Date:  1975-10
  7 in total
  1 in total

1.  Smooth muscle sensitization induced by colchicine: is it an in vitro property of antitubulin agents?

Authors:  J P Famaey; J Fontaine; J Reuse
Journal:  Agents Actions       Date:  1977-07
  1 in total

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