Literature DB >> 1008013

Does the pro-inflammatory factor in lymphocytes (LpIF) explain the role of these cells in acute inflammation?

R R Santos, J G Leme, S H Ferreira, G H Bechara, L Sudo.   

Abstract

Lymphocytes produce a pro-inflammatory factor, which modulates the development of acute inflammation. Injection of lymphocytes or products, obtained from either rats, dogs or rabbits, caused a restoration of inflammatory responses in leukopenic rats which are hyporeactive to various inflammatory stimuli. In vitro incubation of viable lymphocytes with homologous and heterologous anti-lymphocyte sera abolished the ability of the cells to restore the inhibited inflammatory reactions.

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Year:  1976        PMID: 1008013     DOI: 10.1007/bf02026089

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  8 in total

1.  The output of lymphocytes from the thoracic duct of unanaesthetized mice.

Authors:  B M GESNER; J L GOWANS
Journal:  Br J Exp Pathol       Date:  1962-08

2.  The role of the lymphocyte and its products in the propagation of joint disease.

Authors:  C M Pearson; H E Paulus; H I Machleder
Journal:  Ann N Y Acad Sci       Date:  1975-06-13       Impact factor: 5.691

3.  A proinflammatory factor in lymphocytes. Its role in the development of acute, non-immunological inflammatory reactions.

Authors:  J G Leme; G H Bechara; R R Dos Santos
Journal:  Br J Exp Pathol       Date:  1976-08

4.  Suppression of experimentally induced polyarthritis in the rat by heterologous anti-lymphocyte serum.

Authors:  H L Currey; M Ziff
Journal:  Lancet       Date:  1966-10-22       Impact factor: 79.321

5.  2 anti-inflammatory components in antilymphocytic serum.

Authors:  M E Billingham; B V Robinson; J M Gaugas
Journal:  Nature       Date:  1970-07-18       Impact factor: 49.962

6.  Separation of anti-inflammatory and immunosuppressive activities in heterologous antilymphocyte serum.

Authors:  R J Perper; E M Glen; R E Monovich
Journal:  Nature       Date:  1969-07-05       Impact factor: 49.962

7.  An analysis of the effects of some types of anti-lymphocyte sera on contact hypersensitivity and certain models of inflammation.

Authors:  J L Turk; D A Willoughby; J E Stevens
Journal:  Immunology       Date:  1968-05       Impact factor: 7.397

8.  Modulation by lymphocytes of the vascular effects caused by inflammatory mediators and carrageenin in the rat.

Authors:  G H Bechara; L Sudo; R Ribeiro dos Santos; J G Leme
Journal:  Br J Exp Pathol       Date:  1976-10
  8 in total
  4 in total

1.  Lymphocytes and non-immune inflammation [proceedings].

Authors:  J G Leme
Journal:  Agents Actions       Date:  1978-01

2.  Role of lymphocytes in non-immune experimental inflammation.

Authors:  J Garcia-Leme
Journal:  Agents Actions       Date:  1981-12

3.  The inflammatory responses of rats depleted of lymphocytes or with an artificial obstruction of the thoracic duct.

Authors:  L S Sudo; J G Leme
Journal:  Br J Exp Pathol       Date:  1980-04

4.  The proinflammatory function of lymphocytes in non-immune inflammation: effect of steroidal and non-steroidal anti-inflammatory agents.

Authors:  J G Leme; G H Bechara; L S Sudo
Journal:  Br J Exp Pathol       Date:  1977-12
  4 in total

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