Literature DB >> 10080050

Deaths associated with inhalant abuse in Virginia from 1987 to 1996.

S E Bowen1, J Daniel, R L Balster.   

Abstract

Inhalant abuse has existed for a considerable period of time and it is currently one of the most prevalent drug abuse problems in the world. One repercussion from using these compounds is that abuse may result in lethality. In an attempt to better understand the deaths associated with inhalant abuse, the authors surveyed the death records from the Commonwealth of Virginia from 1987 to 1996. Examination of the state records identified 39 deaths related to inhalant abuse during this time period. While no significant increase or decrease in the death rate was observed across the time period investigated, all regions of Virginia were affected, with the rates being highest in the northern and eastern regions of the state. Age of death ranged from 13 to 42 years with the majority of deaths (70%) occurring at 22 years of age or younger. Ninety-five per cent of the individuals were male, with volatile substance abuse deaths accounting for 0.3% of all deaths in males aged 13-22 years. The chief volatile substances used were gas fuels (46%), predominately butane and propane, chlorofluorocarbons (26%), chlorinated hydrocarbons and alkylbenzenes (21%), and other volatile substances including volatile anesthetics. Deaths associated with the abuse of butane and toluene were more likely to be traumatic, but all substances appeared capable of killing directly by their toxic effects, probably through cardiac and/or respiratory mechanisms. The ramifications of these findings for regulation and prevention are addressed.

Entities:  

Mesh:

Substances:

Year:  1999        PMID: 10080050     DOI: 10.1016/s0376-8716(98)00139-2

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  25 in total

1.  Review of toluene action: clinical evidence, animal studies and molecular targets.

Authors:  Silvia L Cruz; María Teresa Rivera-García; John J Woodward
Journal:  J Drug Alcohol Res       Date:  2014

2.  Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes.

Authors:  S L Cruz; R L Balster; J J Woodward
Journal:  Br J Pharmacol       Date:  2000-12       Impact factor: 8.739

3.  Inhalant abuse and dependence among adolescents in the United States.

Authors:  Li-Tzy Wu; Daniel J Pilowsky; William E Schlenger
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2004-10       Impact factor: 8.829

4.  Alterations in rat fetal morphology following abuse patterns of toluene exposure.

Authors:  Scott E Bowen; Susan Irtenkauf; John H Hannigan; Adrianne L Stefanski
Journal:  Reprod Toxicol       Date:  2009-01-21       Impact factor: 3.143

5.  Air Duster abuse causing rapid airway compromise.

Authors:  Amanda Winston; Abed Kanzy; Ghassan Bachuwa
Journal:  BMJ Case Rep       Date:  2015-01-07

6.  Inhalant use and disorders among adults in the United States.

Authors:  Li-Tzy Wu; Christopher L Ringwalt
Journal:  Drug Alcohol Depend       Date:  2006-04-03       Impact factor: 4.492

7.  Evaluating retailer behavior in preventing youth access to harmful legal products a feasibility test.

Authors:  Matthew W Courser; Harold D Holder; David Collins; Knowlton Johnson; Kristen A Ogilvie
Journal:  Eval Rev       Date:  2008-07-25

8.  Preventing youths' use of inhalants and other harmful legal products in frontier Alaskan communities: a randomized trial.

Authors:  Knowlton W Johnson; Stephen R Shamblen; Kristen A Ogilvie; David Collins; Brian Saylor
Journal:  Prev Sci       Date:  2009-12

9.  Neurochemical changes after acute binge toluene inhalation in adolescent and adult rats: a high-resolution magnetic resonance spectroscopy study.

Authors:  Shonagh K O'Leary-Moore; Matthew P Galloway; Andrew P McMechan; Susan Irtenkauf; John H Hannigan; Scott E Bowen
Journal:  Neurotoxicol Teratol       Date:  2009-07-21       Impact factor: 3.763

10.  Abused inhalants enhance GABA-mediated synaptic inhibition.

Authors:  M Bruce MacIver
Journal:  Neuropsychopharmacology       Date:  2009-06-03       Impact factor: 7.853

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