OBJECTIVE: To study fetal weight gain and its association with adverse perinatal events in a serially scanned high-risk population. SUBJECTS AND METHODS: A total of 200 pregnant women considered at increased risk of uteroplacental insufficiency had a total of 1140 scans in the third trimester, with a median of six scans in each pregnancy. The average fetal growth rate was retrospectively calculated for the last 6 weeks to birth, and expressed as daily weight gain in grams per day. Adverse pregnancy outcome was defined as operative delivery for fetal distress, acidotic umbilical artery pH (< 7.15), or admission to the neonatal intensive care unit (NICU). RESULTS: Fetuses with normal outcome in this high-risk pregnancy population had an average antenatal growth rate of 24.2 g/day. Compared to pregnancies with normal outcome, the growth rate was slower in those that required operative delivery for fetal distress (20.9 g/day, p < 0.05) and those that required admission to the NICU (20.3 g/day, p < 0.05). The growth rate in pregnancies resulting in acidotic umbilical artery pH also seemed lower, but this did not reach statistical significance. CONCLUSIONS: Impaired fetal weight gain prior to birth is associated with adverse perinatal events suggestive of growth failure.
OBJECTIVE: To study fetal weight gain and its association with adverse perinatal events in a serially scanned high-risk population. SUBJECTS AND METHODS: A total of 200 pregnant women considered at increased risk of uteroplacental insufficiency had a total of 1140 scans in the third trimester, with a median of six scans in each pregnancy. The average fetal growth rate was retrospectively calculated for the last 6 weeks to birth, and expressed as daily weight gain in grams per day. Adverse pregnancy outcome was defined as operative delivery for fetal distress, acidotic umbilical artery pH (< 7.15), or admission to the neonatal intensive care unit (NICU). RESULTS: Fetuses with normal outcome in this high-risk pregnancy population had an average antenatal growth rate of 24.2 g/day. Compared to pregnancies with normal outcome, the growth rate was slower in those that required operative delivery for fetal distress (20.9 g/day, p < 0.05) and those that required admission to the NICU (20.3 g/day, p < 0.05). The growth rate in pregnancies resulting in acidotic umbilical artery pH also seemed lower, but this did not reach statistical significance. CONCLUSIONS: Impaired fetal weight gain prior to birth is associated with adverse perinatal events suggestive of growth failure.
Authors: Holger W Unger; Stephan Karl; Regina A Wangnapi; Peter Siba; Glen Mola; Jane Walker; Ivo Mueller; Maria Ome; Stephen J Rogerson Journal: Am J Trop Med Hyg Date: 2014-11-10 Impact factor: 2.345
Authors: Francesc Figueras; Eduard Gratacos; Marta Rial; Ilan Gull; Ladislav Krofta; Marek Lubusky; Rogelio Cruz-Martinez; Mónica Cruz-Lemini; Miguel Martinez-Rodriguez; Pamela Socias; Cristina Aleuanlli; Mauro C Parra Cordero Journal: BMJ Open Date: 2017-06-15 Impact factor: 2.692
Authors: Alison M Fung; Danielle L Wilson; Martha Lappas; Mark Howard; Maree Barnes; Fergal O'Donoghue; Stephen Tong; Helen Esdale; Gabrielle Fleming; Susan P Walker Journal: PLoS One Date: 2013-07-24 Impact factor: 3.240
Authors: Nadia Bardien; Clare L Whitehead; Stephen Tong; Antony Ugoni; Susan McDonald; Susan P Walker Journal: PLoS One Date: 2016-01-05 Impact factor: 3.240