Literature DB >> 10079378

Spectrofluorimetric detection of DMBA-induced mouse skin carcinoma.

K Karthikeyan1, V Masilamani, S Govindasamy.   

Abstract

An attempt has been made to evaluate the normal and cancer blood samples of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mouse skin carcinoma by spectrofluorimetric method. Analysis of acetone extracts of plasma, erythrocyte and erythrocyte membrane showed an alteration around 630 nm when excited at 400 nm by cancer samples, compared to normal samples. The ratio of fluorescent intensity at 530 nm/630 nm was found to be decreased in erythrocyte and plasma and increased in erythrocyte membrane. These changes are not detectable in both hemolysates. It has been suggested that erythrocytes may be the carriers of fluorophors that accumulate in cancer tissue and may be useful in the diagnosis and treatment of malignancies.

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Year:  1999        PMID： 10079378     DOI： 10.1053/paor.1999.0046

Source DB:  PubMed          Journal:  Pathol Oncol Res        ISSN： 1219-4956            Impact factor:   3.201


  8 in total

1.  Spectral pathology.

Authors:  G Zonios; R Cothren; J M Crawford; M Fitzmaurice; R Manoharan; J Van Dam; M S Feld
Journal:  Ann N Y Acad Sci       Date:  1998-02-09       Impact factor: 5.691

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3.  Autofluorescence characteristics of oral mucosa.

Authors:  D R Ingrams; J K Dhingra; K Roy; D F Perrault; I D Bottrill; S Kabani; E E Rebeiz; M M Pankratov; S M Shapshay; R Manoharan; I Itzkan; M S Feld
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4.  Detection of adenocarcinoma in Barrett's oesophagus by means of laser induced fluorescence.

Authors:  C S von Holstein; A M Nilsson; S Andersson-Engels; R Willén; B Walther; K Svanberg
Journal:  Gut       Date:  1996-11       Impact factor: 23.059

5.  Characteristic autofluorescence for cancer diagnosis and its origin.

Authors:  Y L Yang; Y M Ye; F M Li; Y F Li; P Z Ma
Journal:  Lasers Surg Med       Date:  1987       Impact factor: 4.025

6.  Chemopreventive effect of Ocimum sanctum on DMBA-induced hamster buccal pouch carcinogenesis.

Authors:  K Karthikeyan; P Ravichandran; S Govindasamy
Journal:  Oral Oncol       Date:  1999-01       Impact factor: 5.337

7.  Characterization of native fluorescence from DMBA-treated hamster cheek pouch buccal mucosa for measuring tissue transformation.

Authors:  N Vengadesan; P Aruna; S Ganesan
Journal:  Br J Cancer       Date:  1998       Impact factor: 7.640

8.  Fluorescence spectroscopic identification of 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.

Authors:  S Balasubramanian; V Elangovan; S Govindasamy
Journal:  Carcinogenesis       Date:  1995-10       Impact factor: 4.944
  8 in total
  2 in total

1.  Erythrocyte Protoporphyrin Fluorescence as a Biomarker to Monitor the Anticancer Effect of Semecarpus Anacardium in DMBA Induced Mammary Carcinoma Rat Model.

Authors:  Haseena Banu Hedayathullah Khan; S Vani; Shanthi Palanivelu; Sachdanandam Panchanadham
Journal:  J Fluoresc       Date:  2015-05-06       Impact factor: 2.217

2.  Restraint stress abates the antioxidant potential of melatonin on dimethyl benz (a) anthracene (DMBA) induced carcinogenesis.

Authors:  Irfana Muqbil; Sabiha Fatima; Asfar S Azmi; Ashwag Saleh Alsharidah; Shahida Aziz Khan; Feda Aljaser; Naheed Banu
Journal:  Med Oncol       Date:  2020-09-29       Impact factor: 3.064
  2 in total

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