| Literature DB >> 10078747 |
W J Weiner1, A Minagar, L M Shulman.
Abstract
Progressive supranuclear palsy (PSP) is a progressive neurodegenerative disorder with no effective treatment. Dopaminergic agents occasionally produce transient symptomatic improvement. The authors report the results of pramipexole treatment (4.5 mg daily) in six patients with PSP (average disease duration, 4.4 years). Patients were treated for 2 months. Patients were evaluated with the Unified Parkinson's Disease Rating Scale, Hoehn and Yahr stage, and Schwab and England Activities of Daily Living Scale at baseline and 2 months. Pramipexole was not efficacious for the symptoms of PSP.Entities:
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Year: 1999 PMID: 10078747 DOI: 10.1212/wnl.52.4.873
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910