Literature DB >> 10077182

Evaluation of behavioral and social issues among Thai HIV vaccine trial volunteers.

D Thapinta1, R A Jenkins, D D Celentano, S Nitayaphan, P Buapunth, A Triampon, P A Morgan, C Khamboonruang, C Suwanarach, Y Yutabootr, S Ruckphaopunt, S Suwankiti, V Tubtong, W Cheewawat, J G McNeil, R A Michael.   

Abstract

Behavioral and social issues were investigated in phase I/II preventive HIV vaccine trial volunteers in Thailand. These included risk behavior, HIV knowledge, distress, and social experiences associated with trial participation. Data were collected at baseline and at 4- and 8-month follow-up visits. Volunteers reported relatively low levels of risk behaviors at baseline and at the follow-up visits. About one fifth reported overtly negative reactions from family or friends. No problems with discrimination in employment, health care, or insurance were reported. Findings add to the evidence suggesting the feasibility of phase I/II prophylactic HIV vaccine trials with low-risk volunteers in Thailand.

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Year:  1999        PMID: 10077182     DOI: 10.1097/00042560-199903010-00015

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr Hum Retrovirol        ISSN: 1077-9450


  5 in total

1.  Testing the waters: Ethical considerations for including PrEP in a phase IIb HIV vaccine efficacy trial.

Authors:  Liza Dawson; Sam Garner; Chuka Anude; Paul Ndebele; Shelly Karuna; Renee Holt; Gail Broder; Jessica Handibode; Scott M Hammer; Magdalena E Sobieszczyk
Journal:  Clin Trials       Date:  2015-04-07       Impact factor: 2.486

Review 2.  Socio-behaviour challenges to phase III HIV vaccine trials in Sub-Saharan Africa.

Authors:  Joalida Smit; Keren Middelkoop; Landon Myer; Graham Lindegger; Leslie Swartz; Soraya Seedat; Tim Tucker; Robin Wood; Linda-Gail Bekker; Dan J Stein
Journal:  Afr Health Sci       Date:  2005-09       Impact factor: 0.927

3.  Social Impacts Among Participants in HIV Vaccine Trial Network (HVTN) Preventive HIV Vaccine Trials.

Authors:  Michele P Andrasik; Fredericka Albertina Sesay; Abby Isaacs; Linda Oseso; Mary Allen
Journal:  J Acquir Immune Defic Syndr       Date:  2020-08-15       Impact factor: 3.731

4.  Experiences of social harm and changes in sexual practices among volunteers who had completed a phase I/II HIV vaccine trial employing HIV-1 DNA priming and HIV-1 MVA boosting in Dar es Salaam, Tanzania.

Authors:  Edith A M Tarimo; Patricia Munseri; Said Aboud; Muhammad Bakari; Fred Mhalu; Eric Sandstrom
Journal:  PLoS One       Date:  2014-03-06       Impact factor: 3.240

5.  Sexual Behaviours and Practices before and after Phase I/II HIV Vaccine Trial: A Qualitative Study among Volunteers in Dar es Salaam Tanzania.

Authors:  Masunga K Iseselo; Edith A M Tarimo; Eric Sandstrom; Asli Kulane
Journal:  Int J Environ Res Public Health       Date:  2020-10-01       Impact factor: 3.390

  5 in total

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