Literature DB >> 10075986

Towards mixed sequence recognition by triple helix formation.

D M Gowers1, K R Fox.   

Abstract

The formation of intermolecular DNA triple helices offers the possibility of designing compounds with extensive sequence recognition properties which may be useful as antigene agents or tools in molecular biology. One major limitation of this approach is that these structures are generally restricted to homo-purine. homopyrimidine target sites. This review describes the strategies that have been employed to overcome this drawback and outlines the potential for triplex formation at mixed sequence DNA targets.

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Year:  1999        PMID： 10075986      PMCID： PMC148358          DOI： 10.1093/nar/27.7.1569

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  26 in total

1.  Improved statistical methods reveal direct interactions between 16S and 23S rRNA.

Authors:  S T Kelley; V R Akmaev; G D Stormo
Journal:  Nucleic Acids Res       Date:  2000-12-15       Impact factor: 16.971

2.  Optimization of alternate-strand triple helix formation at the 5"-TpA-3" and 5"-ApT-3" junctions.

Authors:  P Brodin; J S Sun; J F Mouscadet; C Auclair
Journal:  Nucleic Acids Res       Date:  1999-08-01       Impact factor: 16.971

3.  Measuring motion on DNA by the type I restriction endonuclease EcoR124I using triplex displacement.

Authors:  K Firman; M D Szczelkun
Journal:  EMBO J       Date:  2000-05-02       Impact factor: 11.598

4.  Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme.

Authors:  Iestyn Whitehouse; Chris Stockdale; Andrew Flaus; Mark D Szczelkun; Tom Owen-Hughes
Journal:  Mol Cell Biol       Date:  2003-03       Impact factor: 4.272

5.  Pseudocomplementary PNAs as selective modifiers of protein activity on duplex DNA: the case of type IIs restriction enzymes.

Authors:  Ekaterina Protozanova; Vadim V Demidov; Peter E Nielsen; Maxim D Frank-Kamenetskii
Journal:  Nucleic Acids Res       Date:  2003-07-15       Impact factor: 16.971

6.  Triple-helix formation in the antiparallel binding motif of oligodeoxynucleotides containing N(9)- and N(7)-2-aminopurine deoxynucleosides.

Authors:  S P Parel; C J Leumann
Journal:  Nucleic Acids Res       Date:  2001-06-01       Impact factor: 16.971

7.  Proton exchange and local stability in a DNA triple helix containing a G.TA triad.

Authors:  L Jiang; I M Russu
Journal:  Nucleic Acids Res       Date:  2001-10-15       Impact factor: 16.971

8.  Orientation preferences of backbone secondary amide functional groups in peptide nucleic acid complexes: quantum chemical calculations reveal an intrinsic preference of cationic D-amino acid-based chiral PNA analogues for the P-form.

Authors:  Christopher M Topham; Jeremy C Smith
Journal:  Biophys J       Date:  2006-10-27       Impact factor: 4.033

9.  Selectivity and affinity of triplex-forming oligonucleotides containing 2'-aminoethoxy-5-(3-aminoprop-1-ynyl)uridine for recognizing AT base pairs in duplex DNA.

Authors:  Sadie D Osborne; Vicki E C Powers; David A Rusling; Oliver Lack; Keith R Fox; Tom Brown
Journal:  Nucleic Acids Res       Date:  2004-08-18       Impact factor: 16.971

10.  Cross-linking to an interrupted polypurine sequence with a platinum-modified triplex-forming oligonucleotide.

Authors:  Meghan A Campbell; Paul S Miller
Journal:  J Biol Inorg Chem       Date:  2009-04-07       Impact factor: 3.358
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