Four aristolochic acid esters of rearranged ent-elemane sesquiterpenes from aristolochia heterophylla

Four aristolochic acid esters of ent-elemane type sesquiterpene having a new carbon skeleton, aristophyllides A (1), B (2), C (3), and D (4), were isolated from the stems and roots of Aristolochia heterophylla. The esters were characterized by NMR and MS methods and included is a study of absolute configurations using the CD exciton chirality method.