| Literature DB >> 10075783 |
J R Carney1, J M Krenisky, R T Williamson, J Luo, T J Carlson, V L Hsu, J L Moswa.
Abstract
Bioassay-guided fractionation of the EtOH extract of M. africana, using the in vivo noninsulin-dependent diabetes mellitus db/db mouse model, resulted in the isolation of the new daphnane-type diterpenoid maprouneacin (2). Compound 2 showed potent glucose-lowering properties when given by the oral route.Entities:
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Year: 1999 PMID： 10075783 DOI： 10.1021/np980356c
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050