Literature DB >> 10074907

Synthetic inhibitors of thrombin and factor Xa: from bench to bedside.

J Hauptmann1, J Stürzebecher.   

Abstract

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Year:  1999        PMID： 10074907     DOI： 10.1016/s0049-3848(98)00192-3

Source DB:  PubMed          Journal:  Thromb Res        ISSN： 0049-3848            Impact factor:   3.944


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  19 in total

1.  Genetic algorithm for the design of molecules with desired properties.

Authors:  Stefan Kamphausen; Nils Höltge; Frank Wirsching; Corinna Morys-Wortmann; Daniel Riester; Ruediger Goetz; Marcel Thürk; Andreas Schwienhorst
Journal:  J Comput Aided Mol Des       Date:  2002 Aug-Sep       Impact factor: 3.686

Review 2.  Dabigatran and left atrial appendage thrombus.

Authors:  Alejandro Vidal; Gabriel Vanerio
Journal:  J Thromb Thrombolysis       Date:  2012-11       Impact factor: 2.300

Review 3.  Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.

Authors:  Klaudia Brix; Joseph McInnes; Alaa Al-Hashimi; Maren Rehders; Tripti Tamhane; Mads H Haugen
Journal:  Protoplasma       Date:  2014-11-16       Impact factor: 3.356

4.  Antithrombotic effect of LB-30057 (CI-1028), a new synthetic thrombin inhibitor, in a rabbit model of thrombosis: comparison with inogatran.

Authors:  L Chi; T E Mertz; K L Rogers; N Janiczek; Y W Peng; L Saganek; R F Bousley; P L Juneau; A C Uprichard; K P Gallagher
Journal:  J Thromb Thrombolysis       Date:  2001-02       Impact factor: 2.300

5.  (4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase.

Authors:  S Sperl; U Jacob; N Arroyo de Prada; J Stürzebecher; O G Wilhelm; W Bode; V Magdolen; R Huber; L Moroder
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-09       Impact factor: 11.205

Review 6.  New anticoagulants - promising and failed developments.

Authors:  Job Harenberg; Svetlana Marx; Martin Krejczy; Martin Wehling
Journal:  Br J Pharmacol       Date:  2012-01       Impact factor: 8.739

Review 7.  Direct thrombin inhibitors: pharmacology and application in intensive care medicine.

Authors:  Eva Schaden; Sibylle A Kozek-Langenecker
Journal:  Intensive Care Med       Date:  2010-04-28       Impact factor: 17.440

8.  Thrombin inhibitors identified by computer-assisted multiparameter design.

Authors:  Daniel Riester; Frank Wirsching; Gabriela Salinas; Martina Keller; Michael Gebinoga; Stefan Kamphausen; Christian Merkwirth; Ruediger Goetz; Martin Wiesenfeldt; Jörg Stürzebecher; Wolfram Bode; Rainer Friedrich; Marcel Thürk; Andreas Schwienhorst
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-03       Impact factor: 11.205

Review 9.  Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development.

Authors:  Bengt I Eriksson; Daniel J Quinlan; Jeffrey I Weitz
Journal:  Clin Pharmacokinet       Date:  2009       Impact factor: 6.447

Review 10.  A review of the clinical uses of ximelagatran in thrombosis syndromes.

Authors:  Elizabeth A Bergsrud; Pritesh J Gandhi
Journal:  J Thromb Thrombolysis       Date:  2003-12       Impact factor: 2.300
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