| Literature DB >> 10072785 |
H Neuhaus1, V Rosen, R S Thies.
Abstract
Here we report the cloning and expression of murine BMP-10, a novel member of the TGF-beta superfamily. In the mouse embryo, BMP-10 expression begins at 9.0 d.p.c. and is restricted to the developing heart. Initially, BMP-10 expression localizes to the trabeculated part of the common ventricular chamber and to the bulbus cordis region. After 12.5 d.p.c., additional BMP-10 expression is seen in the atrial wall. The data presented here suggest that BMP-10 plays an important role in trabeculation of the embryonic heart. Copyright 1998 Elsevier Science Ireland Ltd.Entities:
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Year: 1999 PMID: 10072785 DOI: 10.1016/s0925-4773(98)00221-4
Source DB: PubMed Journal: Mech Dev ISSN: 0925-4773 Impact factor: 1.882