Literature DB >> 10072675

Discovery of 6-oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1(6H)- pyridazinebutanoic acid (FK 838): a novel non-xanthine adenosine A1 receptor antagonist with potent diuretic activity.

A Akahane1, H Katayama, T Mitsunaga, T Kato, T Kinoshita, Y Kita, T Kusunoki, T Terai, K Yoshida, Y Shiokawa.   

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Year:  1999        PMID： 10072675     DOI： 10.1021/jm980671w

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  4 in total

1.  Three successive and regiocontroled palladium cross-coupling reactions to easily synthesize novel series of 2,4,6-tris(het)aryl pyrido[1',2':1,5]pyrazolo[3,4-d]pyrimidines.

Authors:  R Belaroussi; A Ejjoummany; A El Hakmaoui; M Akssira; G Guillaumet; S Routier
Journal:  RSC Adv       Date:  2018-01-02       Impact factor: 3.361

Review 2.  Pyrazolo derivatives as potent adenosine receptor antagonists: an overview on the structure-activity relationships.

Authors:  Siew Lee Cheong; Gopalakrishnan Venkatesan; Priyankar Paira; Ramasamy Jothibasu; Alexander Laurence Mandel; Stephanie Federico; Giampiero Spalluto; Giorgia Pastorin
Journal:  Int J Med Chem       Date:  2011-03-07

3.  Regioselective Synthesis of New 2,4-(Het)aryl-3H-pyrido[1',2':1,5]pyrazolo[4,3-d]pyrimidines Involving Palladium-Catalyzed Cross-Coupling Reactions.

Authors:  Abdelaziz Ejjoummany; Rabia Belaroussi; Ahmed El Hakmaoui; Mohamed Akssira; Gérald Guillaumet; Frédéric Buron; Sylvain Routier
Journal:  Molecules       Date:  2018-10-23       Impact factor: 4.411

4.  Synthesis, spectroscopy, crystal structure, TGA/DTA study, DFT and molecular docking investigations of (E)-4-(4-methylbenzyl)-6-styrylpyridazin-3(2H)-one.

Authors:  Fouad El Kalai; Emine Berrin Çınar; Chin-Hung Lai; Said Daoui; Tarik Chelfi; Mustapha Allali; Necmi Dege; Khalid Karrouchi; Noureddine Benchat
Journal:  J Mol Struct       Date:  2020-10-10       Impact factor: 3.196
  4 in total

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