| Literature DB >> 10072640 |
J M Moulds1, M Brai, J Cohen, A Cortelazzo, M Cuccia, M Lin, S Sadallah, J Schifferli, V Bala Subramanian, L Truedsson, G W Wu, F Zhang, J P Atkinson.
Abstract
A total of 100 Chinese blood donors (50 from Shen-Zhen and 50 from Taiwan) were studied by the participants in addition to 9 reference samples. A new nomenclature for the CR1 structural alleles was recommended by the participants which would use a numbering system, e.g. CR1*1. The structural allele frequencies in the Chinese were: CR1*1 (190 kD) 0.96, CR1*2 (220 kD) 0.03, CR1*3 (160 kD) 0.01 and CR1*4 (250 kD) 0.00. The HindIII expression polymorphism was also studied and the high expressing allele had a gene frequency of 0.71 while the low expressor gene frequency was 0.28. Erythrocyte copy numbers were quantified and compared between laboratories with good correlation (R = 0.55-0.88). The mean (+/- SD) erythrocyte copy number was 463 (+/- 229) in the Taiwan donors and 446 (+/- 207) in the Mainland Chinese.Entities:
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Year: 1998 PMID： 10072640 DOI： 10.1159/000019084
Source DB: PubMed Journal: Exp Clin Immunogenet ISSN： 0254-9670