Literature DB >> 10069482

Effect of Cassava on motor co-ordination and neurotransmitter level in the albino rat.

D C Mathangi1, V Mohan, A Namasivayam.   

Abstract

The root of Cassava, a tropical plant, is consumed in the tropics and has been attributed as the cause for various tropical neuropathies. This study aims to discover the neurotoxic effects of chronic cassava consumption of Indian origin and the effect of malnutrition. The assessment is based on the motor co-ordination and brain neurotransmitters in rats. Cassava consumption reduced the motor co-ordination, but the changes in neurotransmitter levels due to cassava consumption (except for 5HT in corpus striatum) was identical with malnutrition-induced changes, indicating that the toxicity of chronic cassava consumption (of Indian origin) is mainly due to the associated protein calorie malnutrition (PCM).

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Year:  1999        PMID： 10069482     DOI： 10.1016/s0278-6915(98)00099-4

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN： 0278-6915            Impact factor:   6.023


  6 in total

1.  On the biomarkers and mechanisms of konzo, a distinct upper motor neuron disease associated with food (cassava) cyanogenic exposure.

Authors:  Roman M Kassa; Nyamabo L Kasensa; Victor H Monterroso; Robert J Kayton; John E Klimek; Larry L David; Kalala R Lunganza; Kazadi T Kayembe; Marina Bentivoglio; Sharon L Juliano; Desire D Tshala-Katumbay
Journal:  Food Chem Toxicol       Date:  2010-06-09       Impact factor: 6.023

2.  Neurochemical and behavioural correlates in cassava-induced neurotoxicity in rats.

Authors:  D C Mathangi; A Namasivayam
Journal:  Neurotox Res       Date:  2000       Impact factor: 3.911

3.  Effect of alpha-ketoglutarate on neurobehavioral, neurochemical and oxidative changes caused by sub-chronic cyanide poisoning in rats.

Authors:  D C Mathangi; R Shyamala; R Vijayashree; K R Rao; A Ruckmani; R Vijayaraghavan; R Bhattacharya
Journal:  Neurochem Res       Date:  2010-12-24       Impact factor: 3.996

Review 4.  Preclinical and clinical research on the toxic and neurological effects of cassava (Manihot esculenta Crantz) consumption.

Authors:  E Rivadeneyra-Domínguez; J F Rodríguez-Landa
Journal:  Metab Brain Dis       Date:  2019-12-04       Impact factor: 3.584

Review 5.  Cyanide and the human brain: perspectives from a model of food (cassava) poisoning.

Authors:  Desire D Tshala-Katumbay; Nadege N Ngombe; Daniel Okitundu; Larry David; Shawn K Westaway; Michael J Boivin; Ngoyi D Mumba; Jean-Pierre Banea
Journal:  Ann N Y Acad Sci       Date:  2016-07-23       Impact factor: 5.691

6.  Effects of Cassava Juice (Manihot esculenta Crantz) on Renal and Hepatic Function and Motor Impairments in Male Rats.

Authors:  Eduardo Rivadeneyra-Domínguez; José Eduardo Pérez-Pérez; Alma Vázquez-Luna; Rafael Díaz-Sobac; Juan Francisco Rodríguez-Landa
Journal:  Toxins (Basel)       Date:  2020-11-09       Impact factor: 4.546
  6 in total

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