Literature DB >> 10069427

Non-coding plasmid DNA induces IFN-gamma in vivo and suppresses autoimmune encephalomyelitis.

G L Boccaccio1, F Mor, L Steinman.   

Abstract

Regulatory sequences used in plasmids for naked DNA vaccination can modulate cytokine production in vivo. We demonstrate here that injection of plasmid DNA can suppress the prototypic T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis, by inducing IFN-gamma.

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Year:  1999        PMID： 10069427     DOI： 10.1093/intimm/11.2.289

Source DB:  PubMed          Journal:  Int Immunol        ISSN： 0953-8178            Impact factor:   4.823


  10 in total

Review 1.  Gene therapy in experimental autoimmune encephalomyelitis.

Authors:  P M Mathisen; V K Tuohy
Journal:  J Clin Immunol       Date:  2000-09       Impact factor: 8.317

2.  Nonviral Abeta DNA vaccine therapy against Alzheimer's disease: long-term effects and safety.

Authors:  Yoshio Okura; Akira Miyakoshi; Kuniko Kohyama; Il-Kwon Park; Matthias Staufenbiel; Yoh Matsumoto
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-12       Impact factor: 11.205

3.  Induction of immunity to neuroblastoma early after syngeneic hematopoietic stem cell transplantation using a novel mouse tumor vaccine.

Authors:  Weiqing Jing; Rimas J Orentas; Bryon D Johnson
Journal:  Biol Blood Marrow Transplant       Date:  2007-03       Impact factor: 5.742

Review 4.  Vaccines for multiple sclerosis: progress to date.

Authors:  Jorge Correale; Mauricio Farez; Wendy Gilmore
Journal:  CNS Drugs       Date:  2008       Impact factor: 5.749

5.  DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response.

Authors:  Avishai Mimran; Felix Mor; Pnina Carmi; Francisco J Quintana; Varda Rotter; Irun R Cohen
Journal:  J Clin Invest       Date:  2004-03       Impact factor: 14.808

6.  Inflammation and the emerging role of the toll-like receptor system in acute brain ischemia.

Authors:  Brenda J Marsh; Susan L Stevens; Brian Hunter; Mary P Stenzel-Poore
Journal:  Stroke       Date:  2008-12-08       Impact factor: 7.914

Review 7.  Antiinfective applications of toll-like receptor 9 agonists.

Authors:  Arthur M Krieg
Journal:  Proc Am Thorac Soc       Date:  2007-07

8.  Targeting innate receptors with MIS416 reshapes Th responses and suppresses CNS disease in a mouse model of multiple sclerosis.

Authors:  Madeleine White; Gill Webster; David O'Sullivan; Sarrabeth Stone; Anne Camille La Flamme
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240

9.  Immunogenic properties of empty pcDNA3 plasmid against zoonotic cutaneous leishmaniasis in mice.

Authors:  Hossein Montakhab-Yeganeh; Reza Shafiei; Mehdi Najm; Leila Masoori; Ashok Aspatwar; Alireza Badirzadeh
Journal:  PLoS One       Date:  2022-02-15       Impact factor: 3.240

Review 10.  Failed, Interrupted, or Inconclusive Trials on Immunomodulatory Treatment Strategies in Multiple Sclerosis: Update 2015-2020.

Authors:  Leoni Rolfes; Marc Pawlitzki; Steffen Pfeuffer; Niklas Huntemann; Heinz Wiendl; Tobias Ruck; Sven G Meuth
Journal:  BioDrugs       Date:  2020-10       Impact factor: 5.807
  10 in total

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