Literature DB >> 10068994

T-cell transformation by Marek's disease virus.

N L Ross1.   

Abstract

Marek's disease virus (MDV) is an avian herpesvirus that causes rapid development of T-cell lymphomas in chickens. The MDV genes currently thought to be involved in lymphomagenesis include a bZIP transactivator that is homologous to fos and jun oncogenes but do not appear to have counterparts in other oncogenic herpesviruses.

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Year:  1999        PMID： 10068994     DOI： 10.1016/s0966-842x(98)01427-9

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  15 in total

1.  Transactivation of latent Marek's disease herpesvirus genes in QT35, a quail fibroblast cell line, by herpesvirus of turkeys.

Authors:  T Yamaguchi; S L Kaplan; P Wakenell; K A Schat
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

2.  Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication.

Authors:  Blanca Lupiani; Lucy F Lee; Xiaoping Cui; Isabel Gimeno; Amy Anderson; Robin W Morgan; Robert F Silva; Richard L Witter; Hsing-Jien Kung; Sanjay M Reddy
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-02       Impact factor: 11.205

3.  The pp38 gene of Marek's disease virus (MDV) is necessary for cytolytic infection of B cells and maintenance of the transformed state but not for cytolytic infection of the feather follicle epithelium and horizontal spread of MDV.

Authors:  I M Gimeno; R L Witter; H D Hunt; S M Reddy; L F Lee; R F Silva
Journal:  J Virol       Date:  2005-04       Impact factor: 5.103

4.  Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the chicken MHC class I molecule BF2*1501.

Authors:  Beibei Sun; Xiaoying Li; Zhenbao Wang; Chun Xia
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2013-01-30

5.  Integrated analyses of genome-wide DNA occupancy and expression profiling identify key genes and pathways involved in cellular transformation by a Marek's disease virus oncoprotein, Meq.

Authors:  Sugalesini Subramaniam; John Johnston; Likit Preeyanon; C Titus Brown; Hsing-Jien Kung; Hans H Cheng
Journal:  J Virol       Date:  2013-06-05       Impact factor: 5.103

6.  Marek's disease virus (MDV) encodes an interleukin-8 homolog (vIL-8): characterization of the vIL-8 protein and a vIL-8 deletion mutant MDV.

Authors:  M S Parcells; S F Lin; R L Dienglewicz; V Majerciak; D R Robinson; H C Chen; Z Wu; G R Dubyak; P Brunovskis; H D Hunt; L F Lee; H J Kung
Journal:  J Virol       Date:  2001-06       Impact factor: 5.103

7.  The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities.

Authors:  Xufang Deng; Xiangdong Li; Yang Shen; Yafeng Qiu; Zixue Shi; Donghua Shao; Yamei Jin; Hongjun Chen; Chan Ding; Li Li; Puyan Chen; Zhiyong Ma
Journal:  Virol J       Date:  2010-11-26       Impact factor: 4.099

8.  Alterations of the MDV oncogenic regions in an MDV transformed lymphoblastoid cell line.

Authors:  E Le Rouzic; P Thoraval; M Afanassieff; Y Cherel; G Dambrine; B Perbal
Journal:  Mol Pathol       Date:  2002-08

9.  Homodimerization of Marek's disease virus-encoded Meq protein is not sufficient for transformation of lymphocytes in chickens.

Authors:  Paulette F Suchodolski; Yoshihiro Izumiya; Blanca Lupiani; Dharani K Ajithdoss; Oren Gilad; Lucy F Lee; Hsing-Jien Kung; Sanjay M Reddy
Journal:  J Virol       Date:  2008-10-29       Impact factor: 5.103

10.  Transcriptional profiling of Marek's disease virus genes during cytolytic and latent infection.

Authors:  Mohammad Heidari; Marianne Huebner; Dmitry Kireev; Robert F Silva
Journal:  Virus Genes       Date:  2008-02-12       Impact factor: 2.332
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