Literature DB >> 10066532

Bacterial enzymatic resistance: beta-lactamases and aminoglycoside-modifying enzymes.

K Bush1, G H Miller.   

Abstract

Numerous novel beta-lactamases and aminoglycoside-modifying enzymes with altered substrate profiles continue to be identified. Plasmid-mediated transmission of many of these enzymes readily occurs due to inclusion of the encoding genes in mobile gene cassettes. Recent crystallographic determinations of the structures of metallo-beta-lactamases and aminoglycoside-modifying enzymes provide the opportunity for the rational design of inhibitors.

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Year:  1998        PMID： 10066532     DOI： 10.1016/s1369-5274(98)80082-9

Source DB:  PubMed          Journal:  Curr Opin Microbiol        ISSN： 1369-5274            Impact factor:   7.934


  7 in total

1.  In vitro and in vivo activities of AM-112, a novel oxapenem.

Authors:  Conor E Jamieson; Peter A Lambert; Iain N Simpson
Journal:  Antimicrob Agents Chemother       Date:  2003-05       Impact factor: 5.191

2.  Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital.

Authors:  Rodrigo E Mendes; Mariana Castanheira; Mark A Toleman; Helio S Sader; Ronald N Jones; Timothy R Walsh
Journal:  Antimicrob Agents Chemother       Date:  2007-04-30       Impact factor: 5.191

3.  Molecular dynamic simulations of the metallo-beta-lactamase from Bacteroides fragilis in the presence and absence of a tight-binding inhibitor.

Authors:  Freddie R Salsbury; Michael W Crowder; Stephen F Kingsmore; James J A Huntley
Journal:  J Mol Model       Date:  2008-11-28       Impact factor: 1.810

4.  The saci_2123 gene of the hyperthermoacidophile Sulfolobus acidocaldarius encodes an ATP-binding cassette multidrug transporter.

Authors:  Nuan Yang; Arnold J M Driessen
Journal:  Extremophiles       Date:  2014-08-20       Impact factor: 2.395

Review 5.  Resistance mechanisms.

Authors:  Yasemin Cag; Hulya Caskurlu; Yanyan Fan; Bin Cao; Haluk Vahaboglu
Journal:  Ann Transl Med       Date:  2016-09

Review 6.  Recent Advances in Multi-Drug Resistance (MDR) Efflux Pump Inhibitors of Gram-Positive Bacteria S. aureus.

Authors:  Jadwiga Handzlik; Anna Matys; Katarzyna Kieć-Kononowicz
Journal:  Antibiotics (Basel)       Date:  2013-02-05

7.  Antibacterial and Antibiotic-Modifying Activity of Methanol Extracts from Six Cameroonian Food Plants against Multidrug-Resistant Enteric Bacteria.

Authors:  Joachim K Dzotam; Victor Kuete
Journal:  Biomed Res Int       Date:  2017-08-20       Impact factor: 3.411
  7 in total

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