Normal and increased functional asymmetries in the craniofacial area.

Normal asymmetry in the area of the craniofacial skeleton can be directional or fluctuating in nature. Directionality can in principle be found in three dimensions: anteroposterior, cranio-caudal, and asymmetries in the left-right dimension. When it comes to directional left right differences, an explanation has been difficult to find, although expressions of this type are obvious. Recent findings made in molecular genetics strongly support the genetic inheritance pattern of laterality. When functionally increased asymmetries of facial structures are concerned, it is often difficult to determine the exact contribution of each factor involved. In the light of recent experimental data, however, it seems that the influence of occlusion on the development of balanced facial structures is highly important during the early periods of life. A review of these factors is given in this article.