Literature DB >> 10065364

Modulation of drug metabolism in infectious and inflammatory diseases.

H Iber1, M B Sewer, T B Barclay, S R Mitchell, T Li, E T Morgan.   

Abstract

During inflammation, expression of various P450 genes is modulated differentially. Both the downregulation of some P450s and the induction of others may be the result of a complex interaction involving inflammatory cytokines, stress hormones, and metabolic perturbations. Our results suggest that NO is not an important mediator for the downregulation of CYP2C11 in rat liver.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10065364     DOI： 10.1081/dmr-100101906

Source DB:  PubMed          Journal:  Drug Metab Rev        ISSN： 0360-2532            Impact factor:   4.518


  13 in total

1.  Accelerated metabolism of voriconazole and its partial reversal by cimetidine.

Authors:  Brad Moriyama; Jason Elinoff; Robert L Danner; Juan Gea-Banacloche; Gennethel Pennick; Michael G Rinaldi; Thomas J Walsh
Journal:  Antimicrob Agents Chemother       Date:  2009-01-26       Impact factor: 5.191

2.  Inflammation and psychotropic drugs: the relationship between C-reactive protein and antipsychotic drug levels.

Authors:  Gudrun Hefner; Mohamed E E Shams; Stefan Unterecker; Tanja Falter; Christoph Hiemke
Journal:  Psychopharmacology (Berl)       Date:  2015-06-03       Impact factor: 4.530

Review 3.  Pharmacokinetic and pharmacodynamic considerations when treating patients with sepsis and septic shock.

Authors:  Peter De Paepe; Frans M Belpaire; Walter A Buylaert
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

4.  Treprostinil Improves Hepatic Cytochrome P450 Activity during Rat Liver Transplantation.

Authors:  Nisanne Ghonem; Junichi Yoshida; Noriko Murase; Stephen C Strom; Raman Venkataramanan
Journal:  J Clin Exp Hepatol       Date:  2012-10-12

5.  Effect of novel anti-inflammatory ethanolamine derivatives with antioxidant properties on drug metabolising enzymes.

Authors:  I Andreadou; E A Rekka; P N Kourounakis
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2003 Jan-Mar       Impact factor: 2.441

6.  The potential role of transcription factor aryl hydrocarbon receptor in downregulation of hepatic cytochrome P-450 during sepsis.

Authors:  Mian Zhou; Subir R Maitra; Ping Wang
Journal:  Int J Mol Med       Date:  2008-04       Impact factor: 4.101

7.  Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study.

Authors:  Bhagwat Prasad; Deepak Kumar Bhatt; Katherine Johnson; Revathi Chapa; Xiaoyan Chu; Laurent Salphati; Guangqing Xiao; Caroline Lee; Cornelis E C A Hop; Anita Mathias; Yurong Lai; Mingxiang Liao; William G Humphreys; Sean C Kumer; Jashvant D Unadkat
Journal:  Drug Metab Dispos       Date:  2018-04-25       Impact factor: 3.922

8.  The role of hepatic cytochrome P-450 in sepsis.

Authors:  Asha Jacob; Mian Zhou; Rongqian Wu; Ping Wang
Journal:  Int J Clin Exp Med       Date:  2009-08-25

Review 9.  Mechanisms of clinically relevant drug interactions associated with tacrolimus.

Authors:  Uwe Christians; Wolfgang Jacobsen; Leslie Z Benet; Alfonso Lampen
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

10.  Elevated Clozapine Blood Concentrations After Second COVID-19 Vaccination With Spikevax (COVID-19 Vaccine Moderna).

Authors:  Christian Knöchel; Gudrun Hefner; Thomas Stiehl; Walter Schmidbauer
Journal:  J Clin Psychopharmacol       Date:  2022-01-28       Impact factor: 3.118
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.