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Literature DB >> 10051438

Activation of integrin-beta3-associated syk in platelets.

Abstract

Published data suggest that the tyrosine kinase syk participates in platelet signalling through the integrin alphaIIbbeta3. Our data show an association of syk and integrin beta3 in immunoprecipitates from unstimulated and stimulated platelets. We detected syk in anti-beta3 precipitates and, conversely, beta3 in anti-syk precipitates. In vitro kinase assays with anti-beta3 precipitates demonstrated that syk activity was enhanced in ADP-stimulated platelets.

Entities: Chemical Gene

Mesh：

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Year: 1999 PMID： 10051438 PMCID： PMC1220102

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

21 in total

1. Association of the 72-kDa protein-tyrosine kinase PTK72 with the B cell antigen receptor.

Authors: J E Hutchcroft; M L Harrison; R L Geahlen
Journal: J Biol Chem Date: 1992-04-25 Impact factor: 5.157

Review 2. Cellular functions regulated by Src family kinases.

Authors: S M Thomas; J S Brugge
Journal: Annu Rev Cell Dev Biol Date: 1997 Impact factor: 13.827

3. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors: U K Laemmli
Journal: Nature Date: 1970-08-15 Impact factor: 49.962

4. Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3.

Authors: E A Clark; S J Shattil; M H Ginsberg; J Bolen; J S Brugge
Journal: J Biol Chem Date: 1994-11-18 Impact factor: 5.157

5. A deletion in the gene for glycoprotein IIb associated with Glanzmann's thrombasthenia.

Authors: C D Burk; P J Newman; S Lyman; J Gill; B S Coller; M Poncz
Journal: J Clin Invest Date: 1991-01 Impact factor: 14.808

6. Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol.

Authors: J M Oliver; D L Burg; B S Wilson; J L McLaughlin; R L Geahlen
Journal: J Biol Chem Date: 1994-11-25 Impact factor: 5.157

7. Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets.

Authors: E A Clark; J S Brugge
Journal: Mol Cell Biol Date: 1993-03 Impact factor: 4.272

8. Protein tyrosine kinase p59fyn is associated with the T cell receptor-CD3 complex in functional human lymphocytes.

Authors: M Gassmann; M Guttinger; K E Amrein; P Burn
Journal: Eur J Immunol Date: 1992-01 Impact factor: 5.532

9. Association with B-cell-antigen receptor with protein-tyrosine kinase p72syk and activation by engagement of membrane IgM.

Authors: T Yamada; T Taniguchi; C Yang; S Yasue; H Saito; H Yamamura
Journal: Eur J Biochem Date: 1993-04-01

10. Two human antibodies reacting with different epitopes on integrin beta 3 of platelets and endothelial cells.

Authors: V Jallu; M Diaz-Ricart; A Ordinas; M Pico; G Vezon; A T Nurden
Journal: Eur J Biochem Date: 1994-06-15

1 in total

Review 1. Cancer development, progression, and therapy: an epigenetic overview.

Authors: Sibaji Sarkar; Garrick Horn; Kimberly Moulton; Anuja Oza; Shannon Byler; Shannon Kokolus; McKenna Longacre
Journal: Int J Mol Sci Date: 2013-10-21 Impact factor: 5.923

1 in total