Literature DB >> 1005113

Bone marrow ribonucleic acid polymerase. Effect of testosterone on nucleotide incorporation into nuclear RNA.

L E Valladares, P E Cañas, J J Minguell.   

Abstract

The incorporation of 3H-UTP into RNA by isolated rat bone marrow nuclei is stimulated by testosterone. This effect is hormone and tissue specific. Using alpha-amanitine and different ionic strength conditions it was found that testosterone enhances preferentially RNA polymerase I activity. The sedimentation pattern of RNA isolated from bone marrow nuclei shows that the synthesis of RNA species within the 14-30 S range is mainly stimulated by the hormone.

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Year:  1976        PMID： 1005113      PMCID： PMC343152          DOI： 10.1093/nar/3.11.3077

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  10 in total

1.  DNA-dependent RNA polymerase levels during the response of human peripheral lymphocytes to phytohemagglutinin.

Authors:  J A Jaehning; C C Stewart; R G Roeder
Journal:  Cell       Date:  1975-01       Impact factor: 41.582

Review 2.  Molecular mechanism of action of the male sex hormones.

Authors:  J J Minguell; W D Sierralta
Journal:  J Endocrinol       Date:  1975-05       Impact factor: 4.286

3.  Characterization of a nuclear receptor for testosterone in rat bone marrow.

Authors:  L Valladares; J Minguell
Journal:  Steroids       Date:  1975-01       Impact factor: 2.668

4.  RNA polymerase activity and uterine growth: Differential stimulation by estradiol, estriol, and nafoxidine.

Authors:  J W Hardin; J H Clark; S R Glasser; E J Peck
Journal:  Biochemistry       Date:  1976-04-06       Impact factor: 3.162

5.  Ribonuclease activity in rat bone marrow nuclei.

Authors:  W Sierralta; J Minguell
Journal:  Biochem Biophys Res Commun       Date:  1970-10-09       Impact factor: 3.575

6.  Characteristics of erythropoietin-induced RNA from foetal mouse liver erythropoietic cell cultures and the effects of 5-fluorodeoxyuridine.

Authors:  A G Nicol; D Conkie; W G Lanyon; C E Drewienkiewicz; R Williamson; J Paul
Journal:  Biochim Biophys Acta       Date:  1972-08-25

7.  Effect of methyltestosterone on the nucleic acid metabolism of rat bone marrow cells.

Authors:  J Minguell; A Garavagno; J Yanez
Journal:  Proc Soc Exp Biol Med       Date:  1971-11

8.  Tables for estimating sedimentation through linear concentration gradients of sucrose solution.

Authors:  C R McEwen
Journal:  Anal Biochem       Date:  1967-07       Impact factor: 3.365

9.  Androgen "receptor" in rat liver: cytosol "receptor" deficiency in pseudohermaphrodite male rats.

Authors:  B Milin; A K Roy
Journal:  Nat New Biol       Date:  1973-04-25

10.  Role of DNA-dependent RNA polymerase 3 in the transcription of the tRNA and 5S RNA genes.

Authors:  R Weinmann; R G Roeder
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205
  10 in total

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