Literature DB >> 10050221

The effect of midazolam on persistent postoperative nausea and vomiting.

T Di Florio1, C R Goucke.   

Abstract

The effect of intravenous midazolam on persistent postoperative nausea and vomiting (PONV) was compared to placebo in a prospective randomized double-blind study. Twenty patients aged 18 to 82 years with persistent PONV resistant to standard anti-emetics and present for greater than six hours were randomized to receive either an intravenous infusion of midazolam 1.0 mg/h or placebo. Nausea (P = 0.04), vomiting (P = 0.02) and the use of rescue anti-emetics (P = 0.003) were significantly less in the midazolam group. We conclude that low-dose intravenous infusion of midazolam significantly reduces persistent PONV.

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Year:  1999        PMID： 10050221     DOI： 10.1177/0310057X9902700107

Source DB:  PubMed          Journal:  Anaesth Intensive Care        ISSN： 0310-057X            Impact factor:   1.669


  9 in total

1.  Antiemetic effects of midazolam added to fentanyl-ropivacaine patient-controlled epidural analgesia after subtotal gastrectomy: A prospective, randomized, double-blind, controlled trial.

Authors:  Sioh Kim; Jeongwon Seo; Younghoon Jeon
Journal:  Curr Ther Res Clin Exp       Date:  2010-10

2.  Comparison of palonosetron with combined palonosetron and midazolam for preventing postoperative nausea and vomiting after laparoscopic cholecystectomy.

Authors:  Eun Kyung Choi; Sang-Jin Park; Chanyang Park; Jung A Lim
Journal:  Medicine (Baltimore)       Date:  2021-08-20       Impact factor: 1.817

3.  Treatment of established postoperative nausea and vomiting: a quantitative systematic review.

Authors:  Faranak Kazemi-Kjellberg; Iris Henzi; Martin R Tramèr
Journal:  BMC Anesthesiol       Date:  2001       Impact factor: 2.217

4.  Effect of Sub hypnotic Doses of Propofol and Midazolam for Nausea and Vomiting During Spinal Anesthesia for Cesarean Section.

Authors:  Sousan Rasooli; Farnaz Moslemi; Arash Khaki
Journal:  Anesth Pain Med       Date:  2014-09-16

5.  Effect of fentanyl on nausea and vomiting in cesarean section under spinal anesthesia: a randomized controlled study.

Authors:  Dong Wook Shin; Yeojung Kim; Boohwi Hong; Seok-Hwa Yoon; Chae Seong Lim; Sookyoung Youn
Journal:  J Int Med Res       Date:  2019-08-27       Impact factor: 1.671

6.  Management of postoperative nausea and vomiting: focus on palonosetron.

Authors:  Neil A Muchatuta; Michael J Paech
Journal:  Ther Clin Risk Manag       Date:  2009-03-26       Impact factor: 2.423

7.  Comparison of efficacy between palonosetron-midazolam combination and palonosetron alone for prevention of postoperative nausea and vomiting in patients undergoing breast surgery and patient controlled analgesia: A prospective, randomized, double-blind study: A CONSORT-compliant study.

Authors:  Jeong-Min Hong; Yun-Hee Han; Dowon Lee; Boo Young Hwang; Jiseok Baik; Ah Reum Cho; Hyeon Jeong Lee; Eunsoo Kim
Journal:  Medicine (Baltimore)       Date:  2021-07-02       Impact factor: 1.817

8.  Comparing the preventive effect of midazolam and midazolam-dexamethasone on postoperative nausea and vomiting in elective middle ear surgery.

Authors:  Sayed Morteza Heidari; Reihanak Talakoub; Zahra Yaraghi
Journal:  Adv Biomed Res       Date:  2012-05-11

9.  Minimum Effective dose of Dexamethasone in Combination with Midazolam as Prophylaxis against Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy.

Authors:  Rakhi Gupta; Shashi Srivastava; Sanjay Dhiraaj; Puja P Chovatiya
Journal:  Anesth Essays Res       Date:  2018 Apr-Jun
  9 in total

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