| Literature DB >> 10048722 |
J Kaspareit1, S Rittinghausen.
Abstract
In a 24-months study, the spontaneous tumour spectrum of the Hsd:Sprague-Dawley stock was examined. Pituitary gland tumours were found in 20% of the males and 39% of the females. This relatively low incidence, compared to other SPRD stocks, had little effect on the survival of females (50%), due to the high incidence (76%) of mammary gland tumours (predominantly fibroadenomas) that resulted in unscheduled sacrifices of many females. Other common neoplasms in Hsd:Sprague-Dawley rats were benign medullary tumours (27% in males, 11% in females), C-cell adenomas (23% in males, 28% in females), and endometrial stromal polyps (22% in females).Entities:
Mesh：
Year: 1999 PMID： 10048722 DOI： 10.1016/S0940-2993(99)80079-7
Source DB: PubMed Journal: Exp Toxicol Pathol ISSN： 0940-2993