| Literature DB >> 10047576 |
L Chen1.
Abstract
Recent structure determinations of high order complexes of eukaryotic transcription factors bound to DNA have revealed that residues from their DNA-binding domains are involved in protein-protein interactions between distinct factors. Protein-protein interactions between transactivation domains and coactivators have also been characterized in a number of recently determined structures. These studies support the combinatorial mechanism of transcription regulation in eukaryotic cells and multicellular organisms.Mesh：
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Year: 1999 PMID： 10047576 DOI： 10.1016/s0959-440x(99)80007-4
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809