Literature DB >> 1004657

Human neoplastic cells in tissue culture: two established cell lines derived from giant cell tumor and fibrosarcoma.

V Thurzo, M Popovic, J Matoska, M Blasko, M Grófová, A Lizonová, M Steno.   

Abstract

The establishment and cultivation of two human neoplastic cell lines is described. The cell line B-5GT was derived from bone giant cell tumor and B-6FS from poorly differentiated fibrosarcoma. In comparison to the normal skin fibroblasts both cell lines have a potential for "indefinite" multiplication in vitro and they exhibit growth properties which are associated with malignant transformation. The parameters investigated included cell morphology, chromosome characteristics, terminal cell density, growth pattern, residual DNA synthesis and growth in soft agar. Both cell lines exhibited human karyotype with aneuploidy and differed in their karyotype from each other.

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Year:  1976        PMID： 1004657

Source DB:  PubMed          Journal:  Neoplasma        ISSN： 0028-2685            Impact factor:   2.575


  6 in total

1.  Effect of syndecan-1 overexpression on mesenchymal tumour cell proliferation with focus on different functional domains.

Authors:  F Zong; E Fthenou; J Castro; B Péterfia; I Kovalszky; L Szilák; G Tzanakakis; K Dobra
Journal:  Cell Prolif       Date:  2009-10-13       Impact factor: 6.831

2.  Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins.

Authors:  F Rorsman; M Bywater; T J Knott; J Scott; C Betsholtz
Journal:  Mol Cell Biol       Date:  1988-02       Impact factor: 4.272

3.  Specific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migration.

Authors:  Fang Zong; Eleni Fthenou; Filip Mundt; Tünde Szatmári; Ilona Kovalszky; László Szilák; David Brodin; George Tzanakakis; Anders Hjerpe; Katalin Dobra
Journal:  PLoS One       Date:  2011-06-23       Impact factor: 3.240

4.  Syndecan-1 and FGF-2, but not FGF receptor-1, share a common transport route and co-localize with heparanase in the nuclei of mesenchymal tumor cells.

Authors:  Fang Zong; Eleni Fthenou; Nina Wolmer; Péter Hollósi; Ilona Kovalszky; László Szilák; Carolin Mogler; Gustav Nilsonne; Georgios Tzanakakis; Katalin Dobra
Journal:  PLoS One       Date:  2009-10-05       Impact factor: 3.240

5.  Heparin regulates B6FS cell motility through a FAK/actin cytoskeleton axis.

Authors:  Kallirroi Voudouri; Dragana Nikitovic; Aikaterini Berdiaki; Dionysios J Papachristou; John Tsiaoussis; Demetrios A Spandidos; Aristides M Tsatsakis; George N Tzanakakis
Journal:  Oncol Rep       Date:  2016-08-30       Impact factor: 3.906

6.  Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1.

Authors:  Tünde Szatmári; Filip Mundt; Ashish Kumar-Singh; Lena Möbus; Rita Ötvös; Anders Hjerpe; Katalin Dobra
Journal:  BMC Cell Biol       Date:  2017-12-08       Impact factor: 4.241
  6 in total

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