Literature DB >> 1004500

Pyruvate kinase activity and gluconeogenesis in rat liver after glycogen depletion with nicotinic acid.

F J Moreno, M Benito, F Sánchez-Medina, J M Medina, F Mayor.   

Abstract

Nicotinic acid administration, which depletes liver glycogen, leads to an increase of both pyruvate kinase L and phosphoenolypyruvate carboxykinase in liver by a factor of nearly two. The former is not prevented by either cycloheximide or actinomycin D. L-Cysteine, an allosteric inhibitor of pyruvate kinase L, favors gluconeogenesis from lactate in both nicotinic acid treated and starved animals.

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Year:  1976        PMID： 1004500     DOI： 10.1007/bf01837058

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  19 in total

1.  Energy cost of gluconeogenesis in rat liver.

Authors:  J R Williamson; A Jákob; R Scholz
Journal:  Metabolism       Date:  1971-01       Impact factor: 8.694

2.  Pyruvate kinase. Classes of regulatory isoenzymes in mammalian tissues.

Authors:  J Carbonell; J E Felíu; R Marco; A Sols
Journal:  Eur J Biochem       Date:  1973-08-01

3.  Two interconvertible forms of L-type pyruvate kinase from rat liver.

Authors:  J C Van Berkel; J F Koster; W C Hülsmann
Journal:  Biochim Biophys Acta       Date:  1973-01-12

4.  Crystallization, characterization and metabolic regulation of two types of pyruvate kinase isolated from rat tissues.

Authors:  T Tanaka; Y Harano; F Sue; H Morimura
Journal:  J Biochem       Date:  1967-07       Impact factor: 3.387

5.  Regulation of the pyruvate kinase of an established rat liver cell line (RLC) in culture by insulin, glucose and serum.

Authors:  L E Gerschenson; M Andersson
Journal:  Biochem Biophys Res Commun       Date:  1971-06-18       Impact factor: 3.575

6.  Acute effects of nicotinic acid in the rat I. Plasma and liver lipids and blood glucose.

Authors:  L A Carlson; E R Nye
Journal:  Acta Med Scand       Date:  1966-04

7.  The effect of nicotinic acid on glycolytic carbohydrate breakdown in the liver.

Authors:  H P Ammon; C J Estler
Journal:  Life Sci       Date:  1967-03-15       Impact factor: 5.037

8.  Regulation of rat liver pyruvate kinase. The effect of preincubation, pH, copper ions, fructose 1,6-diphosphate and dietary changes on enzyme activity.

Authors:  E Bailey; F Stirpe; C B Taylor
Journal:  Biochem J       Date:  1968-07       Impact factor: 3.857

9.  Carbohydrate metabolism of the perfused rat liver.

Authors:  B D Ross; R Hems; R A Freedland; H A Krebs
Journal:  Biochem J       Date:  1967-11       Impact factor: 3.857

10.  Gluconeogenesis in the perfused rat liver.

Authors:  R Hems; B D Ross; M N Berry; H A Krebs
Journal:  Biochem J       Date:  1966-11       Impact factor: 3.857
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  1 in total

1.  LC-MS proteomics analysis of the insulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism.

Authors:  Geert Depuydt; Fang Xie; Vladislav A Petyuk; Arne Smolders; Heather M Brewer; David G Camp; Richard D Smith; Bart P Braeckman
Journal:  J Proteome Res       Date:  2014-03-03       Impact factor: 4.466
  1 in total

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