Literature DB >> 10037038

Monosomy X as the sole cytogenetic abnormality in acute lymphoblastic leukemia: a report of two new patients.

J L Bueno1, A Watson, M G Dainton, D M Hughes, S Killick, J G Treleaven, G J Swansbury.   

Abstract

Monosomy X as the sole acquired cytogenetic abnormality is usually found in myeloid hematological malignancies, especially those with myelodysplastic features. Only three cases of acute lymphoblastic leukemia (ALL) with this abnormality have been previously reported. We add two cases to this series and comment on the likelihood of a tumor suppressor gene being located on the X chromosome.

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Year:  1999        PMID: 10037038     DOI: 10.3109/10428199909167401

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN: 1026-8022


  1 in total

1.  Sex chromosome loss after allogeneic hematopoietic stem cell transplant in patients with hematologic neoplasms: a diagnostic dilemma for clinical cytogeneticists.

Authors:  Zhenya Tang; L Jeffrey Medeiros; C Cameron Yin; Wei Wang; Xinyan Lu; Ken H Young; Joseph D Khoury; Guilin Tang
Journal:  Mol Cytogenet       Date:  2016-08-08       Impact factor: 2.009

  1 in total

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