Literature DB >> 1003631

A case of uric acid renal stone with hypouricemia caused by tubular reabsorptive defect of uric acid.

K Kawabe, T Murayama, I Akaoka.   

Abstract

A 60-year-old man had a uric acid stone in the kidney and laboratory findings of hypouricemia (1.1 mg. per 100 ml.) and increased uric acid clearance (43 ml. per minute per 1.73 m.2). Clearance of uric acid exceeded the endogenous creatinine clearance after administration of pyrazinamide, an inhibitor of renal tubular secretion of uric acid. It was suggested that our patient had a complete defective mechanism for uric acid reabsorption, resulting in hyperuricuria and the formation of the uric acid stone.

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Year:  1976        PMID: 1003631     DOI: 10.1016/s0022-5347(17)58973-9

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  3 in total

1.  Acute renal failure due to uric acid nephropathy in a patient with renal hypouricemia.

Authors:  C M Erley; R R Hirschberg; W Hoefer; K Schaefer
Journal:  Klin Wochenschr       Date:  1989-03-01

2.  Normal urate transport into erythrocytes in familial renal hypouricemia and in the Dalmatian dog.

Authors:  P Vinay; A Gattereau; B Moulin; A Gougoux; G Lemieux
Journal:  Can Med Assoc J       Date:  1983-03-01       Impact factor: 8.262

3.  Familial hypouricaemia associated with renal tubular uricosuria and uric acid calculi: case report.

Authors:  J M Hedley; P J Phillips
Journal:  J Clin Pathol       Date:  1980-10       Impact factor: 3.411

  3 in total

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